Impact of preeclampsia on ventricular repolarization indices
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Churchill Livingstone Inc Medical Publishers
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: Because of cardiac hypertrophy and electrophysiological alterations associated with preeclampsia, worsening of preexisting arrhythmias or occurrence of de novo arrhythmias are common in patients with preeclampsia. Tp-e/QT and Tpe/QTc ratios are accepted as reliable indexes for predicting ventricular arrhythmias. In this study, we examined the impact of preeclampsia on ventricular repolarization indices in patients with preeclampsia by using the QT, QTc and Tp-e interval, Tp-e/QTratio, and Tp-e/QTc ratio. Methods: We analyzed electrocardiographic recordings of sixty pregnant women with preeclampsia and thirty age-matched healthy pregnant women. Women presenting with preeclampsia were divided into 2 groups and classified as early (gestational age < 34 weeks at clinical onset) or late (>= 34 weeks) onset preeclampsia. Ventricular repolarization indices were evaluated. Results: The QT and Tp-e intervals were found to be longer in patients with earlyonset preeclampsia compared to patients with late-onset preeclampsia and helthy pregnants (377.6 +/- 23 ms vs 374.3 +/- 15 ms, 362 +/- 15 ms & 82.6 +/- 9.4 ms vs 74.0 +/- 10.6 ms, 68.6 +/- 10 ms). In adition, Tp-e/QT and Tp-e/QTc ratio were significantly higher in this patient population compared to others (0.21 +/- 0.02 vs 0.19 +/- 0.02, 0.18 +/- 0.02 & 0.19 +/- 0.02 vs 0.16 +/- 0.02, 0.15 +/- 0,02, p < 0.05 respectively). Conclusion: Our data showed that preeclampsia has unfavorable effects on electrocardiographic indices of ventricular repolarization compared to healthy pregnant women. This effect is more prominent in patients with early-onset preeclampsia.
Açıklama
Anahtar Kelimeler
Ventricular Repolarization Indices, Preeclampsia
Kaynak
Journal Of Electrocardiology
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
69
