Olanzapine and quetiapine in the prevention of a new mood episode in women with bipolar disorder during the postpartum period: a retrospective cohort study
Küçük Resim Yok
Tarih
2021
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Assoc Brasileira Psiquiatria
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: To examine whether olanzapine and quetiapine are useful in the prevention of a new mood episode during the postpartum period. Methods: Data on 23 patients (n=14 for olanzapine and n=9 for quetiapine) with bipolar disorder who met the criteria for this study were retrospectively gathered. The diagnosis of bipolar disorder was determined by means of the DSM-IV. Results: The mean follow-up period was 33.95 +/- 12.07 weeks. Six (26.1%) of 23 patients experienced recurrent mood episodes during the postpartum period. Four of these six patients were taking olanzapine and two were taking quetiapine. Patients with recurrent mood episodes had a significantly stronger family history of bipolar disorder, higher number of past episodes, and earlier onset and longer duration of illness compared to patients without recurrent mood episodes. Conclusion: Monotherapy with olanzapine or quetiapine can be considered as an alternative to mood stabilizers in preventing the development of new mood episodes after childbirth.
Açıklama
Anahtar Kelimeler
Postpartum Period, Olanzapine, Quetiapine, Bipolar Disorder
Kaynak
Brazilian Journal Of Psychiatry
WoS Q Değeri
Q1
Scopus Q Değeri
Q2
Cilt
43
Sayı
6
