Olanzapine and quetiapine in the prevention of a new mood episode in women with bipolar disorder during the postpartum period: a retrospective cohort study

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dc.contributor.authorUguz, Faruk
dc.contributor.authorKirkas, Aysegul
dc.date.accessioned2024-02-23T14:30:07Z
dc.date.available2024-02-23T14:30:07Z
dc.date.issued2021
dc.departmentNEÜen_US
dc.description.abstractObjective: To examine whether olanzapine and quetiapine are useful in the prevention of a new mood episode during the postpartum period. Methods: Data on 23 patients (n=14 for olanzapine and n=9 for quetiapine) with bipolar disorder who met the criteria for this study were retrospectively gathered. The diagnosis of bipolar disorder was determined by means of the DSM-IV. Results: The mean follow-up period was 33.95 +/- 12.07 weeks. Six (26.1%) of 23 patients experienced recurrent mood episodes during the postpartum period. Four of these six patients were taking olanzapine and two were taking quetiapine. Patients with recurrent mood episodes had a significantly stronger family history of bipolar disorder, higher number of past episodes, and earlier onset and longer duration of illness compared to patients without recurrent mood episodes. Conclusion: Monotherapy with olanzapine or quetiapine can be considered as an alternative to mood stabilizers in preventing the development of new mood episodes after childbirth.en_US
dc.identifier.doi10.1590/1516-4446-2020-1629
dc.identifier.endpage620en_US
dc.identifier.issn1516-4446
dc.identifier.issn1809-452X
dc.identifier.issue6en_US
dc.identifier.pmid33825764en_US
dc.identifier.scopus2-s2.0-85122294074en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage617en_US
dc.identifier.urihttps://doi.org/10.1590/1516-4446-2020-1629
dc.identifier.urihttps://hdl.handle.net/20.500.12452/15025
dc.identifier.volume43en_US
dc.identifier.wosWOS:000760090300011en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Brasileira Psiquiatriaen_US
dc.relation.ispartofBrazilian Journal Of Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPostpartum Perioden_US
dc.subjectOlanzapineen_US
dc.subjectQuetiapineen_US
dc.subjectBipolar Disorderen_US
dc.titleOlanzapine and quetiapine in the prevention of a new mood episode in women with bipolar disorder during the postpartum period: a retrospective cohort studyen_US
dc.typeArticleen_US

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