Novel chiral Tetraazacalix[4]arene[2]triazine-based derivatives as catalysts: enantioselective Michael reaction of nitroolefins and diketones

Küçük Resim Yok

Tarih

2023

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Springer

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

A novel derivatives of tetraazacalix[4] arene[2] triazine-based catalysts for enantioselective Michael addition reactions of nitroolefins and diketones were presented. Chiral moieties were connected to the heteroatom-bridged calix-triazin scaffold by reactions of (S)- or (R)-(+)-1-(1-Naphthyl)ethylamine with tetraazacalix[4]arene[2]triazine. To utilize the catalytic activity of the chiral catalysts, diketones reacted with a wide variety of trans-beta-nitrostyrenes in Toluene, respectively, obtaining the Michael products in excellent yields and enantiomeric excesses (up to 96% yield and 99% ee). [GRAPHICS] .

Açıklama

Anahtar Kelimeler

Asymmetric Synthesis, Michael Addition, Organocatalysis, Stereoselectivity, Tetraazacalix[4]Arene[2]Triazine

Kaynak

Journal Of Inclusion Phenomena And Macrocyclic Chemistry

WoS Q Değeri

Scopus Q Değeri

Q3

Cilt

103

Sayı

5.Haz

Künye