Novel chiral Tetraazacalix[4]arene[2]triazine-based derivatives as catalysts: enantioselective Michael reaction of nitroolefins and diketones
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A novel derivatives of tetraazacalix[4] arene[2] triazine-based catalysts for enantioselective Michael addition reactions of nitroolefins and diketones were presented. Chiral moieties were connected to the heteroatom-bridged calix-triazin scaffold by reactions of (S)- or (R)-(+)-1-(1-Naphthyl)ethylamine with tetraazacalix[4]arene[2]triazine. To utilize the catalytic activity of the chiral catalysts, diketones reacted with a wide variety of trans-beta-nitrostyrenes in Toluene, respectively, obtaining the Michael products in excellent yields and enantiomeric excesses (up to 96% yield and 99% ee). [GRAPHICS] .
Açıklama
Anahtar Kelimeler
Asymmetric Synthesis, Michael Addition, Organocatalysis, Stereoselectivity, Tetraazacalix[4]Arene[2]Triazine
Kaynak
Journal Of Inclusion Phenomena And Macrocyclic Chemistry
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
103
Sayı
5.Haz
