Total oxidant, antioxidant, and paraoxonase levels in babies born to pre-eclamptic mothers

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dc.contributor.authorAltunhan, Huseyin
dc.contributor.authorAnnagur, Ali
dc.contributor.authorKurban, Sevil
dc.contributor.authorErtugrul, Sabahattin
dc.contributor.authorKonak, Murat
dc.contributor.authorOrs, Rahmi
dc.date.accessioned2024-02-23T14:24:30Z
dc.date.available2024-02-23T14:24:30Z
dc.date.issued2013
dc.departmentNEÜen_US
dc.description.abstractAim The aim of this study was to investigate the oxidant-antioxidant status in babies born to pre-eclamptic mothers (BBPM). Material and Methods The paraoxonase (PON)-1, total antioxidant status (TAS), and total oxidant status (TOS) levels were measured in the cord blood and venous blood (7th day) of BBPM (n=31) and babies born to normotensive mothers (n=25). Results The PON-1 and TOS levels in the cord blood and venous blood on the 7th day were not significantly different between the two groups; however, the cord blood TAS levels were higher in BBPM (P=0.001), and the TAS levels in the venous blood were higher in the control group (P=0.021). Furthermore, the cord blood PON-1 levels of babies born to severely pre-eclamptic mothers (n=18) were higher than those of babies born to moderately pre-eclamptic mothers (n=13) (P=0.042). There were no differences in the cord blood TAS and TOS levels and venous blood PON-1, TAS, and TOS levels between babies born to severely and moderately pre-eclamptic mothers. Conclusion The increased TAS levels found in the cord blood of BBPM indicate that the fetus is protected against oxidative damage caused by increased oxidative stress in the mother. To the best of our knowledge, this is the first study in the published work investigating PON-1 levels in BBPM.en_US
dc.identifier.doi10.1111/jog.12026
dc.identifier.endpage904en_US
dc.identifier.issn1341-8076
dc.identifier.issn1447-0756
dc.identifier.issue5en_US
dc.identifier.pmid23551806en_US
dc.identifier.scopus2-s2.0-84880287407en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage898en_US
dc.identifier.urihttps://doi.org/10.1111/jog.12026
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13978
dc.identifier.volume39en_US
dc.identifier.wosWOS:000318246900003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofJournal Of Obstetrics And Gynaecology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntioxidant Activityen_US
dc.subjectNewbornen_US
dc.subjectOxidative Stressen_US
dc.subjectParaoxonase-1en_US
dc.subjectTotal Antioxidant Statusen_US
dc.subjectTotal Oxidant Statusen_US
dc.titleTotal oxidant, antioxidant, and paraoxonase levels in babies born to pre-eclamptic mothersen_US
dc.typeArticleen_US

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