Kronik obstrüktif akciğer hastalıklı olgularda görsel uyarılmış kortikal potansiyeller
Küçük Resim Yok
Tarih
1998
Yazarlar
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
KOAH'da oluşan hipoksik nöropatiyi elektrofizyolojik bir metodla tetkik etmek amacıyla, KOAH tamsı alan 40 hasta ve 26 sağlıklı olguda PR VEP özellikleri belirlendi. Dama taşı şeklinde pattern uyarım verildi. Olguların her bir kareyi görüş açılan 62 dakika idi. PR VEP amplitüd ve P 100 latans değerleri sol ve sağ göz için ayrı ayrı kaydedildi. PR VEP P100 latans değeri KOAH grubunda, kontrol grubuna göre anlamlı olarak uzun bulundu(sırasıyla 113,7± 6,7 ms ve 110,5± 4,4 ms) (p<0.05). KOAH iılarda PR VEP P100 latansı ile hastalık süresi ve yaş arasında korelasyon saptandı. Amplitüd de ise iki grup arasında istatistiksel olarak anlamlı fark yoktu. Sonuç olarak, PR VEP P100 latans gecikmesinin demiyelinizasyon, aksonal dejenerasyon, endonöronal hipoksi, endonöronal mikroanjiopati ve iskemik ileti yetmezliği direnci ile ilgili olabileceği düşünüldü.
To establish the hypoxic neuropathy occured in chronic obsructive pulmonary disease by an electrophysiologic method, we examined the characteristics of PR VEP of 40 patients with chronic obsructive pulmonary disease and 26 healty persons. The sight angle of the cases for one square was 62 minutes. We noted the amplitude of PR VEP and P 100 latency values one by one for the left and right eye. The values PR VEP P 100 latency determined in the group of chronic obsructive pulmonary disease was significantly long when compared with the control group ( 113,7 ± 6,7 ms and 110,5 ± 4,4 ms respectively ). The corelation between the values of PR VEP P 1 00 latency and the age of the patients and the period of the disease was proved in the patients of chronic obsructive pulmonary disease. But there was no significant systatistical difference of amplitude between the patient and healty groups. As a conclusion, we consider the delay of PR VEP P 100 latency was related to demyelinization, axonal degeneration, endoneuronal hypoxi, endoneuronal microangiopathy and the resistance to ischemic conduction failure.
To establish the hypoxic neuropathy occured in chronic obsructive pulmonary disease by an electrophysiologic method, we examined the characteristics of PR VEP of 40 patients with chronic obsructive pulmonary disease and 26 healty persons. The sight angle of the cases for one square was 62 minutes. We noted the amplitude of PR VEP and P 100 latency values one by one for the left and right eye. The values PR VEP P 100 latency determined in the group of chronic obsructive pulmonary disease was significantly long when compared with the control group ( 113,7 ± 6,7 ms and 110,5 ± 4,4 ms respectively ). The corelation between the values of PR VEP P 1 00 latency and the age of the patients and the period of the disease was proved in the patients of chronic obsructive pulmonary disease. But there was no significant systatistical difference of amplitude between the patient and healty groups. As a conclusion, we consider the delay of PR VEP P 100 latency was related to demyelinization, axonal degeneration, endoneuronal hypoxi, endoneuronal microangiopathy and the resistance to ischemic conduction failure.
Açıklama
Anahtar Kelimeler
İskemi, Ischemia, Akciğer hastalıkları-obstrüktif, Lung diseases-obstructive, Uyarılmış potansiyeller-görsel, Evoked potentials-visual
Kaynak
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Sayı
Künye
Yaşar, S. (1998). Kronik obstrüktif akciğer hastalıklı olgularda görsel uyarılmış kortikal potansiyeller. (Yayınlanmamış tıpta uzmanlık tezi) Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Dahili Tıp Bilimleri Göğüs Hastalıkları Anabilim Dalı, Konya.
