Laringo-trakeal rekonstruksiyonda otogreft-homogreft ve dakronun kullanılması: deneysel çalışma
Küçük Resim Yok
Tarih
2003
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Bu çalışmanın amacı otogreft kostal kartilaj (n=12), homogreft kostal kartilaj (n=12) ve alloplastik greft olarak dakron (n=12) kullanılan ratlarda klinik ve histopatolojik inceleme sonuçlarını birbiri ile kıyaslamaktır. Her birinde 12 rat bulunan 3 grup oluşturuldu. I.Grup'da otogreft kostal kartilaj kulanılarak trakeal rekonstrüksiyon yapıldı. II. Grup 'da % 70 alkol içerisinde bekletilerek hazırlanan homogreft kostal kartilaj kullanılarak aynı işlem yapıldı. III. Grup'da ise greft olarak dakron kullanıldı. Deneklerin hepsi postoperatif 90. gün sakrifiye edildi. I. Grup ve Il.Grup'da birer denek komplikasyonlar nedeni ile kaybedildi. Trakeal kesit alanları arasında her üç grup arasında anlamlı bir fark tespit edilmedi (p>0,005). İkinci ve üçüncü gruplarda birinci gruba göre anlamlı derecede fazla inflamatuar hücre infiltrasyonu görüldü (p<0,005). Dakron ve homogreft kullanılan gruplarda epitelizasyon ve neovaskülarizasyon otogreft kullanılana göre dalla düşüktü (p<0,005), ancak epitelizasyon tüm ratlarda oluştu.
The purpose of the present study is to compare the clinic and histopathological results of rats used an autograft costal cartilage (n=12), a homograft costal cartilage (n=12) and dacron alloplastic graft (n=12). Three different groups each consisting 12 rats were composed. In the first group, tracheal reconstruction was made by using autograft costal cartilage. The same surgical procedure was made in the second group by using homograft costal cartilage preserved in the 70% alcohol. In the third group, dacron was used as a graft material. All subjects were sacrified on the 90 day, postoperatively. In the first and second group, one subject was lost because of the complications. There was not a statistically difference among three groups compared tracheal section areas (p>0,005). In the second and third groups, more inflamatuar cell infiltrations were recorded than in the first group (p<0,005). In the groups in which dacron and homograft used, epitelization and neovascularization was less than in the group in which autograft was used (p<0,005), but epitelization was observed in all specimens.
The purpose of the present study is to compare the clinic and histopathological results of rats used an autograft costal cartilage (n=12), a homograft costal cartilage (n=12) and dacron alloplastic graft (n=12). Three different groups each consisting 12 rats were composed. In the first group, tracheal reconstruction was made by using autograft costal cartilage. The same surgical procedure was made in the second group by using homograft costal cartilage preserved in the 70% alcohol. In the third group, dacron was used as a graft material. All subjects were sacrified on the 90 day, postoperatively. In the first and second group, one subject was lost because of the complications. There was not a statistically difference among three groups compared tracheal section areas (p>0,005). In the second and third groups, more inflamatuar cell infiltrations were recorded than in the first group (p<0,005). In the groups in which dacron and homograft used, epitelization and neovascularization was less than in the group in which autograft was used (p<0,005), but epitelization was observed in all specimens.
Açıklama
Anahtar Kelimeler
Otorinolaringoloji., Otorhinolaryngology.
Kaynak
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Baran, Y. (2003). Laringo-trakeal rekonstruksiyonda otogreft-homogreft ve dakronun kullanılması: deneysel çalışma. (Yayınlanmamış tıpta uzmanlık tezi) Necmettin Erbakan Üniversitesi, Meram Tıp Fakültesi Cerrahi Tıp Bilimleri Kulak Burun Boğaz Anabilim Dalı, Konya.
