Is vitamin D insufficiency to blame for recurrent wheezing?
Küçük Resim Yok
Tarih
2014
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Wiley-Blackwell
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
BackgroundVitamin D (VitD) and its metabolites play important roles in the regulation of the respiratory and immune systems. The aim of this study was to examine serum 25(OH) vitamin D [25(OH)D] levels and VitD deficiency on the development of wheezing and clinical features. MethodsThis study was a prospective cross-sectional survey that included a total of 70 infants being followed in the Pediatric Immunology and Allergy Unit at Ondokuz Mayis University. Forty of these infants (patient group), ranging in age from 1 to 3 years, had been diagnosed as wheezy infants; 30 were age-and-gender matched healthy infants (control group). Prior to the study, blood samples were taken from both groups to determine their serum VitD, blood eosinophil, and serum immunoglobulin E (IgE) levels. ResultsThe duration of breastfeeding was similar for both groups. The serum 25(OH)D levels of the patient group were significantly lower than those of the control group. Although there was a negative relationship between 25(OH)D level and IgE((log10)) values for the wheezy infants with VitD deficiency, the control group had a negative relationship between VitD level and IgE((log10)). ConclusionSerum 25(OH)D levels must be evaluated when following wheezy infants, and those with deficiency must be treated with VitD.
Açıklama
Anahtar Kelimeler
Asthma, Allergens, Therapeutics, Vitamin D, 25(Oh)D
Kaynak
International Forum Of Allergy & Rhinology
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
4
Sayı
12
