Is vitamin D insufficiency to blame for recurrent wheezing?
dc.contributor.author | Demirel, Soner | |
dc.contributor.author | Guner, Sukru Nail | |
dc.contributor.author | Celiksoy, Mehmet Halil | |
dc.contributor.author | Sancak, Recep | |
dc.date.accessioned | 2024-02-23T10:17:17Z | |
dc.date.available | 2024-02-23T10:17:17Z | |
dc.date.issued | 2014 | |
dc.department | NEÜ | en_US |
dc.description.abstract | BackgroundVitamin D (VitD) and its metabolites play important roles in the regulation of the respiratory and immune systems. The aim of this study was to examine serum 25(OH) vitamin D [25(OH)D] levels and VitD deficiency on the development of wheezing and clinical features. MethodsThis study was a prospective cross-sectional survey that included a total of 70 infants being followed in the Pediatric Immunology and Allergy Unit at Ondokuz Mayis University. Forty of these infants (patient group), ranging in age from 1 to 3 years, had been diagnosed as wheezy infants; 30 were age-and-gender matched healthy infants (control group). Prior to the study, blood samples were taken from both groups to determine their serum VitD, blood eosinophil, and serum immunoglobulin E (IgE) levels. ResultsThe duration of breastfeeding was similar for both groups. The serum 25(OH)D levels of the patient group were significantly lower than those of the control group. Although there was a negative relationship between 25(OH)D level and IgE((log10)) values for the wheezy infants with VitD deficiency, the control group had a negative relationship between VitD level and IgE((log10)). ConclusionSerum 25(OH)D levels must be evaluated when following wheezy infants, and those with deficiency must be treated with VitD. | en_US |
dc.description.sponsorship | Ondokuz Mayis University [PYO.TIP.1904.10.047] | en_US |
dc.description.sponsorship | Funding sources for the study: Project no. PYO.TIP.1904.10.047 from Ondokuz Mayis University. | en_US |
dc.identifier.doi | 10.1002/alr.21401 | |
dc.identifier.endpage | 985 | en_US |
dc.identifier.issn | 2042-6976 | |
dc.identifier.issn | 2042-6984 | |
dc.identifier.issue | 12 | en_US |
dc.identifier.pmid | 25175821 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 980 | en_US |
dc.identifier.uri | https://doi.org/10.1002/alr.21401 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12452/10521 | |
dc.identifier.volume | 4 | en_US |
dc.identifier.wos | WOS:000346022600006 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Wiley-Blackwell | en_US |
dc.relation.ispartof | International Forum Of Allergy & Rhinology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.subject | Asthma | en_US |
dc.subject | Allergens | en_US |
dc.subject | Therapeutics | en_US |
dc.subject | Vitamin D | en_US |
dc.subject | 25(Oh)D | en_US |
dc.title | Is vitamin D insufficiency to blame for recurrent wheezing? | en_US |
dc.type | Article | en_US |