Is vitamin D insufficiency to blame for recurrent wheezing?

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dc.contributor.authorDemirel, Soner
dc.contributor.authorGuner, Sukru Nail
dc.contributor.authorCeliksoy, Mehmet Halil
dc.contributor.authorSancak, Recep
dc.date.accessioned2024-02-23T10:17:17Z
dc.date.available2024-02-23T10:17:17Z
dc.date.issued2014
dc.departmentNEÜen_US
dc.description.abstractBackgroundVitamin D (VitD) and its metabolites play important roles in the regulation of the respiratory and immune systems. The aim of this study was to examine serum 25(OH) vitamin D [25(OH)D] levels and VitD deficiency on the development of wheezing and clinical features. MethodsThis study was a prospective cross-sectional survey that included a total of 70 infants being followed in the Pediatric Immunology and Allergy Unit at Ondokuz Mayis University. Forty of these infants (patient group), ranging in age from 1 to 3 years, had been diagnosed as wheezy infants; 30 were age-and-gender matched healthy infants (control group). Prior to the study, blood samples were taken from both groups to determine their serum VitD, blood eosinophil, and serum immunoglobulin E (IgE) levels. ResultsThe duration of breastfeeding was similar for both groups. The serum 25(OH)D levels of the patient group were significantly lower than those of the control group. Although there was a negative relationship between 25(OH)D level and IgE((log10)) values for the wheezy infants with VitD deficiency, the control group had a negative relationship between VitD level and IgE((log10)). ConclusionSerum 25(OH)D levels must be evaluated when following wheezy infants, and those with deficiency must be treated with VitD.en_US
dc.description.sponsorshipOndokuz Mayis University [PYO.TIP.1904.10.047]en_US
dc.description.sponsorshipFunding sources for the study: Project no. PYO.TIP.1904.10.047 from Ondokuz Mayis University.en_US
dc.identifier.doi10.1002/alr.21401
dc.identifier.endpage985en_US
dc.identifier.issn2042-6976
dc.identifier.issn2042-6984
dc.identifier.issue12en_US
dc.identifier.pmid25175821en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage980en_US
dc.identifier.urihttps://doi.org/10.1002/alr.21401
dc.identifier.urihttps://hdl.handle.net/20.500.12452/10521
dc.identifier.volume4en_US
dc.identifier.wosWOS:000346022600006en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofInternational Forum Of Allergy & Rhinologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAsthmaen_US
dc.subjectAllergensen_US
dc.subjectTherapeuticsen_US
dc.subjectVitamin Den_US
dc.subject25(Oh)Den_US
dc.titleIs vitamin D insufficiency to blame for recurrent wheezing?en_US
dc.typeArticleen_US

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