Characteristics of the cornea in patients with pseudoexfoliation syndrome
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Consel Brasil Oftalmologia
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: To quantify the morphological alterations in corneal nerve fibers and cells in patients with pseudoexfoliation syndrome (PEX) and their relationship with the presence of hyperreflective endothelial deposits observed using in vivo confocal microscopy. Methods: One eye each of 37 patients with PEX and 20 age-matched healthy control subjects was evaluated by in vivo corneal confocal microscopy. Patients with PEX were further classified into two groups: those with and without hyperreflective endothelial deposits. We evaluated the densities of basal epithelial cells, anterior and posterior stromal keratocytes, and endothelial cells and structure of sub-basal nerve fibers. Results: The mean anterior and posterior stromal keratocyte and endothelial cell densities and corneal sub-basal nerve plexus variables were significantly lower in patients with PEX compared with those in healthy control subjects. The mean basal epithelial cell density did not significantly differ. Conclusion: Eyes with PEX presented decreased corneal sub-basal nerve plexus variables and cell densities in all corneas, except for the mean basal epithelial cell density. Further, a trend of lower corneal sub-basal nerve plexus measurements in patients with hyperreflective endothelial deposits compared with those without endothelial deposits was observed.
Açıklama
Anahtar Kelimeler
Cornea/Physiopathology, Cornea/Innervation, Exfoliation Syndrome/Diagnosis, Confocal Microscopy, Nerve Fibers/Pathology
Kaynak
Arquivos Brasileiros De Oftalmologia
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
78
Sayı
6
