Relationship between the neutrophil-to-lymphocyte ratio in acute pancreatitis and the severity and systemic complications of the disease

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dc.authoridBaşar Cander: 0000-0002-3308-5843en_US
dc.contributor.authorKokulu, Kamil
dc.contributor.authorGünaydın, Yahya Kemal
dc.contributor.authorAkıllı, Nazire Belgin
dc.contributor.authorKöylü, Ramazan
dc.contributor.authorSert, Ekrem Taha
dc.contributor.authorKöylü, Öznur
dc.contributor.authorCander, Başar
dc.date.accessioned2020-01-18T21:04:37Z
dc.date.available2020-01-18T21:04:37Z
dc.date.issued2018
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Acil Tıp Anabilim Dalıen_US
dc.descriptionWOS:000449010500010en_US
dc.descriptionPubMed ID:30381275en_US
dc.description.abstractBackground/Aims: In 80% of the patients, Acute pancreatitis (AP) occurs as a self-limiting disease that does not require any specifictreatment; however, in 20% of the cases it occurs in its clinically severe form that may lead to local or systemic complications. The aimof this prospective study was to examine the relationship between the neutrophil to lymphocyte ratio (NLR) and the systemic complications and severity of AP.Materials and Methods: This prospective study included 100 patients with AP. Age, sex, NLR, Ranson scores and the revised Atlantaclassification of the patients were recorded. The patients were divided into two groups according to the Ranson scores as mild andsevere AP. According to the Revised Atlanta classification, the patients were divided into two groups as mild and moderatesevere AP.Results: According to the Ranson score, NLR at the time of admission and at the 48th hour in the severe group was found to be statistically higher than the mild AP group (p0.01). The receiver operating characteristic (ROC) curve analysis was performed to determinethe cut-off value of NLR at the emergency department in order for it to be used for distinguishing AP patients with and without systemiccomplications. The area under the ROC curve was 0.81. Sensitivity and specificity were 87.50% and 69.05%, respectively, when the NLRcut-off value was 7.13.Conclusion: Neutrophil to lymphocyte ratio is associated with severe AP. We also regard NLR as a valuable parameter for predicting thedevelopment of systemic complications in patients with AP.en_US
dc.identifier.citationCander, B., Kokulu, K., Günaydın, Y. K., Akıllı, N. B., Köylü, R., Sert, E. T., Köylü, O. (2018). Relationship between the neutrophil-to-lymphocyte ratio in acute pancreatitis and the severity and systemic complications of the disease. The Turkish Journal of Gastroenterology, 29, 6, 684-691.en_US
dc.identifier.doi10.5152/tjg.2018.17563en_US
dc.identifier.endpage691en_US
dc.identifier.issn1300-4948en_US
dc.identifier.issn2148-5607en_US
dc.identifier.issue6en_US
dc.identifier.pmid30381275en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage684en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWprNE1qWTJOZz09/relationship-between-the-neutrophil-to-lymphocyte-ratio-in-acute-pancreatitis-and-the-severity-and-systemic-complications-of-the-disease
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1875
dc.identifier.volume29en_US
dc.identifier.wosWOS:000449010500010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPer oral endoscopic myotomyen_US
dc.subjectAchalasiaen_US
dc.subjectAflatoxinen_US
dc.subjectLower esophageal sphincteren_US
dc.titleRelationship between the neutrophil-to-lymphocyte ratio in acute pancreatitis and the severity and systemic complications of the diseaseen_US
dc.typeArticleen_US

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