Mean platelet volume, neutrophil to lyphocyte ratio and platelet to lymphocyte ratio in psoriasis
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Deri Zuhrevi Hastaliklar Dernegi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background and Design: It has been demonstrated that neutrophil and platelet count to lymphocyte ratio may be a useful predictor of systemic inflammation and with prognosis of many cardiovascular diseases, malignancies and chronic inflammatory diseases. To the best of our knowledge, there are no studies investigating neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volume (MPV) values together within the context of psoriasis, a chronic and systemic inflammatory disease. Materials and Methods: In this study, we evaluated 320 patients with psoriasis vulgaris followed up in our outpatient clinic and 200 healthy controls. Results: Leukocyte, neutrophil, platelet, MPV, NLR and PLR values in patients with psoriasis were significantly higher, and lymphocyte count, on the other hand, was significantly lower than in controls. No significant difference was found in MPV, NLR and PLR values between patients with or without a family history and nail and joint involvement. Conclusions: These parameters may be used as cheap and easily applicable methods in predicting which psoriasis patients are under the risk of cardiovascular disease. PLR is a better inflammation marker than MPV and NLR in patients with psoriasis. We did not observe a significant relationship of MPV, NLR and PLR values with disease characteristics, such as severity of disease, joint involvement, nail involvement and duration of disease in patients with psoriasis. Therefore, we believe that there is little information on the extent to which MPV, NLR and PLR might be useful regarding these characteristics.
Açıklama
Anahtar Kelimeler
Psoriasis, Neutrophil/Lymphocyte Ratio, Platelet/Lymphocyte Ratio
Kaynak
Turkderm-Turkish Archives Of Dermatology And Venerology
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
49
Sayı
2
