Mean platelet volume, neutrophil to lyphocyte ratio and platelet to lymphocyte ratio in psoriasis

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dc.contributor.authorUnal, Mehmet
dc.contributor.authorKucuk, Adem
dc.contributor.authorUnal, Gulbahar Urun
dc.contributor.authorBalevi, Sukru
dc.contributor.authorTol, Huseyin
dc.contributor.authorAykol, Caner
dc.contributor.authorUyar, Mehmet
dc.date.accessioned2024-02-23T14:38:22Z
dc.date.available2024-02-23T14:38:22Z
dc.date.issued2015
dc.departmentNEÜen_US
dc.description.abstractBackground and Design: It has been demonstrated that neutrophil and platelet count to lymphocyte ratio may be a useful predictor of systemic inflammation and with prognosis of many cardiovascular diseases, malignancies and chronic inflammatory diseases. To the best of our knowledge, there are no studies investigating neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volume (MPV) values together within the context of psoriasis, a chronic and systemic inflammatory disease. Materials and Methods: In this study, we evaluated 320 patients with psoriasis vulgaris followed up in our outpatient clinic and 200 healthy controls. Results: Leukocyte, neutrophil, platelet, MPV, NLR and PLR values in patients with psoriasis were significantly higher, and lymphocyte count, on the other hand, was significantly lower than in controls. No significant difference was found in MPV, NLR and PLR values between patients with or without a family history and nail and joint involvement. Conclusions: These parameters may be used as cheap and easily applicable methods in predicting which psoriasis patients are under the risk of cardiovascular disease. PLR is a better inflammation marker than MPV and NLR in patients with psoriasis. We did not observe a significant relationship of MPV, NLR and PLR values with disease characteristics, such as severity of disease, joint involvement, nail involvement and duration of disease in patients with psoriasis. Therefore, we believe that there is little information on the extent to which MPV, NLR and PLR might be useful regarding these characteristics.en_US
dc.identifier.doi10.4274/turkderm.57984
dc.identifier.endpage116en_US
dc.identifier.issn2717-6398
dc.identifier.issn2651-5164
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-84940572110en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage112en_US
dc.identifier.urihttps://doi.org/10.4274/turkderm.57984
dc.identifier.urihttps://hdl.handle.net/20.500.12452/16488
dc.identifier.volume49en_US
dc.identifier.wosWOS:000369627900006en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherDeri Zuhrevi Hastaliklar Dernegien_US
dc.relation.ispartofTurkderm-Turkish Archives Of Dermatology And Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPsoriasisen_US
dc.subjectNeutrophil/Lymphocyte Ratioen_US
dc.subjectPlatelet/Lymphocyte Ratioen_US
dc.titleMean platelet volume, neutrophil to lyphocyte ratio and platelet to lymphocyte ratio in psoriasisen_US
dc.typeArticleen_US

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