May Monocyte/HDL Cholesterol Ratio (MHR) and Neutrophil/Lymphocyte Ratio (NLR) Be an Indicator of Inflammation and Oxidative Stress in Patients with Keratoconus?

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dc.contributor.authorKatipoglu, Zeynep
dc.contributor.authorMirza, Enver
dc.contributor.authorOltulu, Refik
dc.contributor.authorKatipoglu, Bilal
dc.date.accessioned2024-02-23T14:20:18Z
dc.date.available2024-02-23T14:20:18Z
dc.date.issued2020
dc.departmentNEÜen_US
dc.description.abstractObjective: To evaluate monocyte/high-density lipoprotein cholesterol ratio (MHR) and neutrophil/lymphocyte ratio (NLR) in patients with keratoconus (KC). Methods: Thirty-one patients with KC (group 1) and 31 healthy control subjects (group 2) were included in the study. All participants' ocular examination findings, clinical and laboratory parameters were obtained from file records and laboratory archives. Results: When group 1 was compared with group 2, MHR (13.7 +/- 5.0 vs. 9.1 +/- 3.7; p < .001) and NLR (2.3 +/- 0.8 vs. 1.7 +/- 0.6; p < .001) were statistically significantly higher in group 1. Optimal MHR cutoff value for KC was calculated as 10.2 with 77.4% sensitivity and 64.5% specificity, and optimal NLR cut-off value for KC was found as 1.9 with 71.4% sensitivity and 55% specificity. Conclusion: MHR and NLR values recognized as indicators of oxidative stress and systemic inflammation were significantly higher in patients with KC compared to the control group.en_US
dc.identifier.doi10.1080/09273948.2019.1611876
dc.identifier.endpage636en_US
dc.identifier.issn0927-3948
dc.identifier.issn1744-5078
dc.identifier.issue4en_US
dc.identifier.pmid31560568en_US
dc.identifier.scopus2-s2.0-85073969557en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage632en_US
dc.identifier.urihttps://doi.org/10.1080/09273948.2019.1611876
dc.identifier.urihttps://hdl.handle.net/20.500.12452/13110
dc.identifier.volume28en_US
dc.identifier.wosWOS:000487908100001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Incen_US
dc.relation.ispartofOcular Immunology And Inflammationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInflammationen_US
dc.subjectKeratoconusen_US
dc.subjectMonocyteen_US
dc.subjectHdl Ratioen_US
dc.subjectNeutrophilen_US
dc.subjectLymphocyte Ratioen_US
dc.subjectOxidative Stressen_US
dc.titleMay Monocyte/HDL Cholesterol Ratio (MHR) and Neutrophil/Lymphocyte Ratio (NLR) Be an Indicator of Inflammation and Oxidative Stress in Patients with Keratoconus?en_US
dc.typeArticleen_US

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