Çocukluk çağı alopesi areatalı olgularımızın geriye dönük değerlendirilmesi
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Dosyalar
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Alopesi areata (AA)lı olguların yaklaşık %20si çocuklardır. Çocukluk çağında görülen alopesi areata ile ilgili sınırlı bilgi bulunmaktadır. Kliniğimizde takip edilen AAlı çocuk olguların demografik özelliklerini, hastalık tedavilerini ve takiplerini incelemeyi amaçladık. Gereç ve Yöntem: Yaşları 16 ve altında olan 110 AA hastasına ait veriler geriye dönük olarak incelendi. Yaş, cinsiyet, hastalık başlangıç yaşı, hastalık süresi, AA tipi ve başlangıç yeri, tırnak tutulumu, eşlik eden dermatoz veya sistemik hastalık varlığı, laboratuvar testleri, AA tedavileri ve takip edildikleri döneme ait bilgiler değerlendirildi. Bulgular: Olguların % 46,4ü kadın, %53,6sı erkekti. Yaş ortalamaları 10,35 yıldı. Hastalık başlangıç yaşı 8,65 yıldı. AA başlangıç yeri % 83,6 olguda scalp, % 5,4 olguda kaş, %5,4 olguda vücut kılları, %2,7 olguda kirpik, %2,7 olguda kaş ve kirpikti. Hastalık tutulum tipi %73,4 olguda AA, %19 olguda alopesi totalis, %5,4 olguda alopesi üniversalis, %1,8 olguda ofiyazisti. Tırnak tutulumu %36,3 olguda mevcuttu. Nevüs flammeus %2,7 olguda mevcuttu. Hastalık süresi ortalama 17,02 aydı. Eşlik eden dermatoz %2,7 olguda vitiligo, %6,3 olguda atopik dermatitti. Eşlik eden sistemik hastalık %1,8 olguda otoimmün tiroidit, %2,7 olguda Down sendromuydu. Tiroid otoantikorları olguların %0,9unda yüksekti. Olguların %4,5inde hipotiroidi, %0,9unda hipertiroidi saptandı. Olguların %24,5ine topikal kortikosteroid losyon, %30,9una antralin, %0,9una minoksidil %2lik losyon, %0,9una kalsipotriol losyon, %1,8ine topikal kalsinörin inhibitörü, %10una intralezyonel kortikosteroid tedavisi verildi. Topikal tedaviye dirençli %15,4 olguda sistemik kortikosteroid ve PUVA tedavisine geçildi. Olguların %14,5inde topikal tedaviler değişik kombinasyonlarda kullanıldı. Olguların %34,5inde remisyon gözlendi. Ortalama remisyon süresi 12,2 aydı. Olguların %26,3ünde ortalama 2 kez nüks gözlendi. Sonuç: Sonuçlarımızın, ülkemizdeki AAlı çocuk olguların epidemiyolojik verilerine katkıda bulunacağını düşünüyoruz. (Türkderm 2013; 47: 158- 60)
Background and Design: Approximately 20% of alopecia areata (AA) cases are children. There is limited information about childhood AA. We aimed to examine demographic features, treatments and prognosis of children with AA followed in our clinic. Materials and Methods: We retrospectively analyzed the records of 110 AA patients 16 years of age or older. Data on age, gender, age at disease onset, duration of the disease, types of AA and onset area, nail involvement, accompanying systemic and dermatological diseases, laboratory tests, treatments and the prognosis, and follow-up period were evaluated. Results: 46.4% of subjects were female and 53.6% were male.The mean age was 10.35 years. The age at disease onset was 8.65 years. Primary onset areas of AA were: scalp in 83.6% of patients, - eyebrows - in 5.4%, - body hair - in 5.4%, - eyelashes - in 2.7%, and eyebrows and eyelashes in 2.7% of patients. Types of the disease were: AA in 73,4% cases, - alopecia totalis -in 19%, - alopecia universalis - in 5.4%, and ophiaisis in 1.8% of subjects. Nail involvement and nevus flammeus were observed in 36.3% and 27% of subjects, respectively. The mean disease duration was 17.02 months. The accompanying dermatoses were: vitiligo in 2.7% of cases and atopic dermatitis in 6.3% of cases. The accompanying systemic diseases were: autoimmüne thyroiditis and Down syndrome in in 1.8% and 2.7% of patients, respectively. Thyroid autoantibodies were found to be high in 0.9% of subjects. We have treated 24.5%of patients with topical corticosteroid lotion, - 30.9%- with anthralin, - 0.9%- with 2% minoxidil lotion, - 0.9%- with calcipotriol lotion, - 1.8%- with topical calcineurin inhibitors, and 10% of cases with intralesional corticosteroids. We have treated 15.4% of subjects, who were resistant to topical treatment, with systemic corticosteroids and PUVA therapy. 14.5% of patients received different combinations of topical treatments. Remission was observed in 34.5% of cases. The mean remission duration was 12.2 months. On average, two relapses occurred in 26.3% of subjects. Conclusion: We assume that our results will contribute to epidemiologic data on childhood AA in our country. (Turkderm 2013; 47: 158-60)
Background and Design: Approximately 20% of alopecia areata (AA) cases are children. There is limited information about childhood AA. We aimed to examine demographic features, treatments and prognosis of children with AA followed in our clinic. Materials and Methods: We retrospectively analyzed the records of 110 AA patients 16 years of age or older. Data on age, gender, age at disease onset, duration of the disease, types of AA and onset area, nail involvement, accompanying systemic and dermatological diseases, laboratory tests, treatments and the prognosis, and follow-up period were evaluated. Results: 46.4% of subjects were female and 53.6% were male.The mean age was 10.35 years. The age at disease onset was 8.65 years. Primary onset areas of AA were: scalp in 83.6% of patients, - eyebrows - in 5.4%, - body hair - in 5.4%, - eyelashes - in 2.7%, and eyebrows and eyelashes in 2.7% of patients. Types of the disease were: AA in 73,4% cases, - alopecia totalis -in 19%, - alopecia universalis - in 5.4%, and ophiaisis in 1.8% of subjects. Nail involvement and nevus flammeus were observed in 36.3% and 27% of subjects, respectively. The mean disease duration was 17.02 months. The accompanying dermatoses were: vitiligo in 2.7% of cases and atopic dermatitis in 6.3% of cases. The accompanying systemic diseases were: autoimmüne thyroiditis and Down syndrome in in 1.8% and 2.7% of patients, respectively. Thyroid autoantibodies were found to be high in 0.9% of subjects. We have treated 24.5%of patients with topical corticosteroid lotion, - 30.9%- with anthralin, - 0.9%- with 2% minoxidil lotion, - 0.9%- with calcipotriol lotion, - 1.8%- with topical calcineurin inhibitors, and 10% of cases with intralesional corticosteroids. We have treated 15.4% of subjects, who were resistant to topical treatment, with systemic corticosteroids and PUVA therapy. 14.5% of patients received different combinations of topical treatments. Remission was observed in 34.5% of cases. The mean remission duration was 12.2 months. On average, two relapses occurred in 26.3% of subjects. Conclusion: We assume that our results will contribute to epidemiologic data on childhood AA in our country. (Turkderm 2013; 47: 158-60)
Açıklama
Anahtar Kelimeler
Dermatoloji, Alopesi Areata, Çocukluk Çağı
Kaynak
Türkderm-Deri Hastalıkları ve Frengi Arşivi
WoS Q Değeri
Scopus Q Değeri
Cilt
47
Sayı
3
Künye
Daye, M., Doğan, S., Balevi, S., Mevlitoğlu, I. (2013). Çocukluk çağı alopesi areatalı olgularımızın geriye dönük değerlendirilmesi. Turkderm, 47, 3, 158-160.
