Bioactive constituents of Lathyrus czeczottianus and ethyl acetate and water extracts and their biological activities: An endemic plant to Turkey
Küçük Resim Yok
Tarih
2021
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Lathyrus species are economically important as food, fodder, and folk medicine. The antioxidant properties (radical scavenging effectiveness, reducing power potentials, metal chelating ability, phosphomolydenum capacity) phytochemical characterization (phenolic composition), and enzyme inhibition abilities of the water and ethyl acetate extracts of Lathyrus czeczottianus (LC) were tested. The phenolic ingradients of LC extracts were evaluated by HPLC-DAD (High-performance liquid chromatography with diode array detector). Chlorogenic acid, epicatechin, and benzoic acid were found as main phenolic compounds in both extracts. Generally, the water extract revealed strong antioxidant potential. The antioxidant effectiveness could be explained by high total phenolic level in the extract. Regarding enzyme inhibitory results, the ethyl acetate extract indicated good inhibitory activities on cholinesterase (for AChE: Acetylccholinesterase 1.15 mg galathamine equivalents (GALAE/g extract) and for BChE: Butyrylcholinesterase 0.19 mg GALAE/g extrac), tyrosinase (54.48 mg kojic acid equivalents (KAE/g)), and alpha-amylase (0.34 mmol acarbose equivalents (ACEs/g)), while the water extract had just good inhibition on alpha-glucosidase (6.49 mmol ACEs/g). In conclusion, L. czeczottianus could be good valuable of bioactive molecules for pharmaceuticals, food and agriculture, and nutraceutical applications. (C) 2020 SAAB. Published by Elsevier B.V. All rights reserved.
Açıklama
Anahtar Kelimeler
Lathyrus, Antioxidant, Hplc, Phenolic Compounds, Enzyme Inhibition
Kaynak
South African Journal Of Botany
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
143
