The ocular surface findings in alopecia areata patients: clinical parameters and impression cytology
Küçük Resim Yok
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose The objective of this study was to examine the effects of alopecia areata (AA) on the ocular surface and conjunctival cytology. Methods A total of 48 subjects were included in the present study. Twenty-three subjects were assigned to group 1 as the patient group, and 25 healthy individuals were included in group 2 as the control group. The ocular surface examination was performed, and the right eyes of all participants were included in the analysis. Both groups underwent the following tests for evaluation of ocular surface: tear break-up time (TBUT), Schirmer I test, Ocular Surface Disease Index (OSDI), and conjunctival impression cytology (CIC). Results obtained from the tests were then analyzed and compared between the groups. Results The mean TBUT value was significantly lower in Group 1 compared to Group 2 (4.96 +/- 3.4 vs 10.52 +/- 4.8 s) (p < 0.001). There was no significant difference between Group 1 and Group 2 in terms of the mean Schirmer I test score (p = 0.129). The mean OSDI score was higher in Group 1 compared to Group 2 (15.48 +/- 10.4 vs 9.61 +/- 13.4), but the difference between both groups was not statistically significant (p = 0.1). The mean CIC score was statistically significantly higher in Group 1 than in Group 2 (1.65 +/- 0.7 vs 0.52 +/- 0.5) (p < 0.001). Conclusion The results of this study showed that AA was correlated with significant disturbances in conjunctival cytology and the tear function.
Açıklama
Anahtar Kelimeler
Dry Eye, Alopecia Areata, Tear Break-Up Time, Schirmer I Test, Osdi, Conjunctival Impression Cytology
Kaynak
International Ophthalmology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
42
Sayı
1
