The ocular surface findings in alopecia areata patients: clinical parameters and impression cytology

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dc.contributor.authorOltulu, Pembe
dc.contributor.authorOltulu, Refik
dc.contributor.authorTurk, Huseyin Bugra
dc.contributor.authorTurk, Nazli
dc.contributor.authorKilinc, Fahriye
dc.contributor.authorBelviranli, Selman
dc.contributor.authorMirza, Enver
dc.date.accessioned2024-02-23T13:56:11Z
dc.date.available2024-02-23T13:56:11Z
dc.date.issued2022
dc.departmentNEÜen_US
dc.description.abstractPurpose The objective of this study was to examine the effects of alopecia areata (AA) on the ocular surface and conjunctival cytology. Methods A total of 48 subjects were included in the present study. Twenty-three subjects were assigned to group 1 as the patient group, and 25 healthy individuals were included in group 2 as the control group. The ocular surface examination was performed, and the right eyes of all participants were included in the analysis. Both groups underwent the following tests for evaluation of ocular surface: tear break-up time (TBUT), Schirmer I test, Ocular Surface Disease Index (OSDI), and conjunctival impression cytology (CIC). Results obtained from the tests were then analyzed and compared between the groups. Results The mean TBUT value was significantly lower in Group 1 compared to Group 2 (4.96 +/- 3.4 vs 10.52 +/- 4.8 s) (p < 0.001). There was no significant difference between Group 1 and Group 2 in terms of the mean Schirmer I test score (p = 0.129). The mean OSDI score was higher in Group 1 compared to Group 2 (15.48 +/- 10.4 vs 9.61 +/- 13.4), but the difference between both groups was not statistically significant (p = 0.1). The mean CIC score was statistically significantly higher in Group 1 than in Group 2 (1.65 +/- 0.7 vs 0.52 +/- 0.5) (p < 0.001). Conclusion The results of this study showed that AA was correlated with significant disturbances in conjunctival cytology and the tear function.en_US
dc.identifier.doi10.1007/s10792-021-01991-y
dc.identifier.endpage12en_US
dc.identifier.issn0165-5701
dc.identifier.issn1573-2630
dc.identifier.issue1en_US
dc.identifier.pmid34331623en_US
dc.identifier.scopus2-s2.0-85111551702en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage7en_US
dc.identifier.urihttps://doi.org/10.1007/s10792-021-01991-y
dc.identifier.urihttps://hdl.handle.net/20.500.12452/11114
dc.identifier.volume42en_US
dc.identifier.wosWOS:000679773500002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDry Eyeen_US
dc.subjectAlopecia Areataen_US
dc.subjectTear Break-Up Timeen_US
dc.subjectSchirmer I Testen_US
dc.subjectOsdien_US
dc.subjectConjunctival Impression Cytologyen_US
dc.titleThe ocular surface findings in alopecia areata patients: clinical parameters and impression cytologyen_US
dc.typeArticleen_US

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