Trakeobronşial amiloidoz
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Tarih
2015
Yazarlar
Dergi Başlığı
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Cilt Başlığı
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Sistemik tutulum olmadan lokalize pulmoner amiloidozis; nodüler parankimal opasiteler, diffüz parankimal opasiteler veya trakeobronşial amiloidozis (TBA) şeklinde görülebilmektedir. TBA daha ziyade erkeklerde, 5
veya 6. dekatta görülen bir durum olup, trakeobronşial ağaçtaki bening
lezyonların %1 kadarıdır. TBA, immun globulin hafif zincirden oluşan amiloid materyelin submukozal plaklar ve/veya polipoid tümorler şeklinde
birikimi ile karakterizedir ve ilerleyici hastalık sonucu hava yolu obstrüksiyonuna yol açabilir. Tedavide başlıca lazer eksiyonu olmak üzere tekrarlayan eksizyonel tedaviler açık cerrahiye tercih edilmektedir. Bu yazımızda
lokalize TBA tanısı alan bir erkek olgu nadir görülmesi sebebi ile sunuldu.
Localized pulmonary amyloidosis without systemic involvement differentiates as nodular parenchymal opacities, diffuse parenchymal opacities, or tracheobronchial amyloidosis (TBA). TBA is a condition mostly seen in males aged up to 50–60 years, accounting for approximately 1% of benign lesions in the tracheobronchial tree. TBA is characterized by the accumulation of the amyloid material comprising immunoglobulin light chain (AL), which are observed as submucosal plaques and/or polypoid tumors; progressive form of tracheobronchial amyloidosis can lead to airway obstruction. Repeated excisional treatments, mainly laser treatment is preferable to open surgery. Here, we have presented the case of a patient diagnosed with the rarely occurring localized TBA.
Localized pulmonary amyloidosis without systemic involvement differentiates as nodular parenchymal opacities, diffuse parenchymal opacities, or tracheobronchial amyloidosis (TBA). TBA is a condition mostly seen in males aged up to 50–60 years, accounting for approximately 1% of benign lesions in the tracheobronchial tree. TBA is characterized by the accumulation of the amyloid material comprising immunoglobulin light chain (AL), which are observed as submucosal plaques and/or polypoid tumors; progressive form of tracheobronchial amyloidosis can lead to airway obstruction. Repeated excisional treatments, mainly laser treatment is preferable to open surgery. Here, we have presented the case of a patient diagnosed with the rarely occurring localized TBA.
Açıklama
Anahtar Kelimeler
Amiloidoz, Pulmoner, Trakeobronşial, Amyloidosis, Pulmonary, Tracheobronchial
Kaynak
İstanbul Medical Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
16
Sayı
3
Künye
Demirbaş, S., Kutlu O., Sakin A. (2015). Trakeobronşial amiloidoz. İstanbul Medical Journal, 16, 3, 119-121.
