Böbrek taşı olan ve olmayan hastaların idrar kültürlerinde üreyen etkenler ve antibiyotik duyarlılıkları
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Tarih
2015
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Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada, üroloji polikliniğine idrar yolu infeksiyon semptomları ile başvuran, görüntüleme tetkiklerinde böbrek taşı tespit edilen ve edilmeyen hasta gruplarının idrar kültürlerinde üreyen etken ve antibiyogram duyarlılık sonuçlarının karşılaştırılması amaçlanmıştır. Gereç ve Yöntemler: Kasım 2010 - Haziran 2013 tarihleri arasında üroloji polikliniğine idrar yolu infeksiyon semptomları ile başvuran 15-50 yaş arası hastalardan alınan idrar örnekleri Merkez Mikrobiyoloji Laboratuarında mikrobiyolojik açıdan değerlendirildi. Laboratuar bilgi sistemi veritabanından tarama yapılarak idrar kültürlerinde 105 koloni üzerinde bakteri üremesi olan hastaların idrar örnekleri çalışmaya dâhil edildi. Hastalar böbrek taşı olan (Grup I) ve olmayan (Grup II) olarak 2 gruba ayrıldı. Mikroorganizmaların tanımlanması ve antibiyotik duyarlılıkları tam otomatik cihaz ile yapıldı. Bulgular: Çalışmaya toplam 2882 hastanın idrar kültür sonuçları dâhil edildi. İdrar kültürlerinin 441 (%15.3)inde 105 koloni üzerinde bakteri üremesi tespit edildi. Bunların 119 (%27)u Grup I, 322 (%73)si Grup IIye ait sonuçlar idi. Grup Ideki hastalarda Acinetobacter spp. ve Enterobacter spp., Grup IIdeki hastalarda E. coli. ve Klebsiella spp. mikroorganizmalar daha yüksek oranda izole edilmiş olup istatistiki olarak anlamlı bulunmuştur. Enterokok türü mikroorganizmaların antibiyotik duyarlılık oranlarının karşılaştırılmasında ise Grup I hastalarda, direnç oranlarındaki yükseklik siprofloksasin ve gentamisin için istatistikî olarak anlamlı bulunmuştur. Enterobactericeae türü mikroorganizmaların antibiyotik duyarlılık oranlarındaki farklılık istatistikî olarak anlamlı bulunmamıştır. İzole edilen diğer mikroorganizmaların sayısı yeterli olmadığından antibiyotik duyarlılık oranları karşılaştırılmamıştır. Sonuç: Acinetobacter gibi dirençli infeksiyon etkeni mikroorganizmaların böbrek taşı olan hastalarda daha yüksek oranda izole edildiği gözlenmiş olup, tedavi öncesinde ve tamamlanmasından sonra mikroorganizmaların tespit edilmesi ve duyarlılık testlerinin değerlendirilmesi için idrar kültürleri yapılmalıdır.
Objective: We aim to compare the antibiogram sensitivity results and the isolated bacteria in urine cultures of patients who applied to our clinic with symptoms of urinary tract infection and imaging surveys detected kidney stones or no kidney stones. Material and Methods: Urine samples gathered from patients between the age of 15 and 50 who visited our urology polyclinic with symptoms of urinary tract infection between November 2010 and June 2013. Microbiological aspects of these samples were evaluated in the Central Microbiology Lab. Urine samples that isolated bacteria which more than 105 colonies in performed urine culture of patients with scanning the database of laboratory information system were included in the study. Patients were separated into two groups: those with kidney stones (Group I) and those without kidney stones (Group II). Identification of the microorganisms and their sensitivity to antibiotics were measured with fully automatic (VITEK 2, Biomerieux, France) device. Results: Urine culture results of 2882 patients were analyzed retrospectively. The samples of 441 (15.3%) patients demonstrated a proliferation of bacteria colonies above 105 . 119 patients (27%) had kidney stones (Group I) and 322 (73%) patients did not (Group II).Among the patients with kidney stones, some microorganisms were isolated in a higher percentage (Table I) and the high ratios of Acinetobacter spp. and Enterobacter spp. isolations were statistically significant (p>0.01). Among the patients without kidney stones, certain microorganisms were isolated in higher ratios (Table I) and high ratios of E. coli. And Klebsiella spp. isolations were statistically significant (p>0.01). The variations in the antibiotic sensitivities of Enterobactericeae microorganisms was not statistically significant. In the comparison of antibiotic sensitivity ratios of Enterococcus type bacteria, the high ratios of resistance was found statistically significant for ciprofloxacin and gentamicin in patients with kidney stones (p>0.01). The other isolated microorganisms were not in sufficient numbers and thus, their ratios of sensitivity to antibiotics were not compared. Conclusion: In this study, it is observed that certain microorganisms such as Acinetobacter that lead to antibiotic-resistant infections were isolated in higher percentages in patients with kidney stones. Also, urine cultures need to be produced in order to detect the microorganisms and evaluate the sensitivity tests before and after the completion of antimicrobial treatment.
Objective: We aim to compare the antibiogram sensitivity results and the isolated bacteria in urine cultures of patients who applied to our clinic with symptoms of urinary tract infection and imaging surveys detected kidney stones or no kidney stones. Material and Methods: Urine samples gathered from patients between the age of 15 and 50 who visited our urology polyclinic with symptoms of urinary tract infection between November 2010 and June 2013. Microbiological aspects of these samples were evaluated in the Central Microbiology Lab. Urine samples that isolated bacteria which more than 105 colonies in performed urine culture of patients with scanning the database of laboratory information system were included in the study. Patients were separated into two groups: those with kidney stones (Group I) and those without kidney stones (Group II). Identification of the microorganisms and their sensitivity to antibiotics were measured with fully automatic (VITEK 2, Biomerieux, France) device. Results: Urine culture results of 2882 patients were analyzed retrospectively. The samples of 441 (15.3%) patients demonstrated a proliferation of bacteria colonies above 105 . 119 patients (27%) had kidney stones (Group I) and 322 (73%) patients did not (Group II).Among the patients with kidney stones, some microorganisms were isolated in a higher percentage (Table I) and the high ratios of Acinetobacter spp. and Enterobacter spp. isolations were statistically significant (p>0.01). Among the patients without kidney stones, certain microorganisms were isolated in higher ratios (Table I) and high ratios of E. coli. And Klebsiella spp. isolations were statistically significant (p>0.01). The variations in the antibiotic sensitivities of Enterobactericeae microorganisms was not statistically significant. In the comparison of antibiotic sensitivity ratios of Enterococcus type bacteria, the high ratios of resistance was found statistically significant for ciprofloxacin and gentamicin in patients with kidney stones (p>0.01). The other isolated microorganisms were not in sufficient numbers and thus, their ratios of sensitivity to antibiotics were not compared. Conclusion: In this study, it is observed that certain microorganisms such as Acinetobacter that lead to antibiotic-resistant infections were isolated in higher percentages in patients with kidney stones. Also, urine cultures need to be produced in order to detect the microorganisms and evaluate the sensitivity tests before and after the completion of antimicrobial treatment.
Açıklama
Anahtar Kelimeler
Böbrek taşı, İdrar kültürü, Antibiyotik duyarlılıkları, Kidney stones, Urine culture, Sensitivity to antibiotics
Kaynak
Yeni Üroloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
10
Sayı
2
Künye
Balasar, M., Kandemir, A., Doğan, M., Ünlü, M. Z., Pişkin, M. M. (2015). Böbrek taşı olan ve olmayan hastaların idrar kültürlerinde üreyen etkenler ve antibiyotik duyarlılıkları. Yeni Üroloji Dergisi, 10, 2, 40-45.
