Kronik Hepatit B Hastaları ve İnaktif Hepatit B Virusu Taşıyıcılarında Depresyon, Anksiyete Düzeyleri ve Yaşam Kalitesinin Değerlendirilmesi
Yükleniyor...
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada kronik hepatit B (KHB) hastaları ve inaktif hepatit B virusu (HBV) taşıyıcılarında sağlıklı kontrol grubuna göre anksiyete, depresyon ve yaşam kalitesi skorlarının karşılaştırılması, HBV infeksiyonu olan kişilerin takip ve tedavisi sırasında multidisipliner yaklaşımların gerekliliğinin gösterilmesi amaçlandı. Yöntemler: Çalışma Ağustos 2013-Ağustos 2014 tarihleri arasında Selçuk Üniversitesi, Tıp Fakültesi, İnfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Polikliniği'ne başvuran 100 KHB hastası, 100 inaktif HBV taşıyıcısı ve 100 sağlıklı kontrol olmak üzere toplam 300 kişi üzerinde yapıldı. Tüm katılımcılara anksiyete ve depresyonu değerlendirmek amacıyla Hastane Anksiyete ve Depresyon (HAD) Ölçeği ve yaşam kalitelerini değerlendirmek amacıyla "Short Form-36" (SF-36) uygulandı. Bulgular: HAD Ölçeğine göre taşıyıcı grupta anksiyete riski kontrol grubundan yüksek bulundu (p0.031). Hasta grubu (p0.031) ve taşıyıcı grupta (p0.046) depresyon riski kontrol grubuna göre yüksek bulundu. Hasta grubu ve taşıyıcı grup arasında anksiyete riski ve depresyon riski açısından anlamlı bir fark yoktu (p0.05). Hasta grubu (p0.015), taşıyıcı grup (p0.035) ve kontrol grubunda (p0.001) kadın hastalarda anksiyete riskinin erkek hastalara göre yüksek olduğu görüldü. Hasta grubu (p0.037) ve taşıyıcı grupta (p0.038) kadın hastalarda depresyon riskinin yüksek olduğu görüldü. Tüm olguların medeni durumları, aile tipi, yaşadıkları yerle anksiyete ve depresyon riskleri arasında fark bulunmadı (p0.05). Yaşam kalitesi parametrelerinden genel sağlık, fiziksel rol güçlüğü ve vitalite skorları, inaktif HBV taşıyıcıları ve KHB hastalarında kontrol grubuna göre düşük bulundu (p<0.05). Sonuçlar: HBV ile kronik olarak infekte kişilerin takip ve tedavileri sırasında ruhsal durumları göz ardı edilmemelidir. Saptanan psikiyatrik bozuklukların etkin şekilde tedavi edilmesi bu olguların sağlıkla ilişkili yaşam kalitelerinin artmasını sağlayacak ve tedaviye olan uyumlarını artıracaktır.
Objective: The objective of this study was to compare the anxiety, depression and quality of life scores of chronic hepatitis B (CHB) patients and inactive hepatitis B virus (HBV) carriers with healthy control subjects and to demonstrate the need for a multidisciplinary approach in the follow-up and treatment of patients with HBV infection. Methods: The study was carried out by comparing 200 subjects including 100 CHB patients and 100 inactive HBV carriers, who were admitted to the Outpatient Clinic of Infectious Diseases and Clinical Microbiology Department, Faculty of Medicine, Selcuk University between August 2013 and August 2014 with 100 healthy control subjects. All subjects were given Hospital Anxiety and Depression (HAD) Scale and Short Form-36 (SF-36) to assess their quality of life. Results: Based on the HAD Scale, anxiety risk among the carriers was higher than the control group (p0.031). Depression risk in the patient (p0.031) and carrier groups (p0.046) were higher than the control group. There was no significant difference between the patient and carrier groups with regard to anxiety risk or depression risk (p0.05). Females had higher anxiety risk in the patient (p0.015), carrier (p0.035) and control (p0.001) groups. Depression risk was also higher in females in the patient (p0.037) and carrier (p0.038) groups. There were no significant relations between marital status, family type, place of living and anxiety and depression risks (p0.05). Three quality of life parameters including general health, role limitations due to physical health and vitality scores in the inactive HBV carriers and CHB patients were lower than those of the control group (p0.05). Conclusions: Psychological state of the patients who are chronically infected with HBV should not be neglected during treatment and follow-up. If a psychiatric disturbance is identified, effective treatment will increase quality of life and improve compliance to treatment.
Objective: The objective of this study was to compare the anxiety, depression and quality of life scores of chronic hepatitis B (CHB) patients and inactive hepatitis B virus (HBV) carriers with healthy control subjects and to demonstrate the need for a multidisciplinary approach in the follow-up and treatment of patients with HBV infection. Methods: The study was carried out by comparing 200 subjects including 100 CHB patients and 100 inactive HBV carriers, who were admitted to the Outpatient Clinic of Infectious Diseases and Clinical Microbiology Department, Faculty of Medicine, Selcuk University between August 2013 and August 2014 with 100 healthy control subjects. All subjects were given Hospital Anxiety and Depression (HAD) Scale and Short Form-36 (SF-36) to assess their quality of life. Results: Based on the HAD Scale, anxiety risk among the carriers was higher than the control group (p0.031). Depression risk in the patient (p0.031) and carrier groups (p0.046) were higher than the control group. There was no significant difference between the patient and carrier groups with regard to anxiety risk or depression risk (p0.05). Females had higher anxiety risk in the patient (p0.015), carrier (p0.035) and control (p0.001) groups. Depression risk was also higher in females in the patient (p0.037) and carrier (p0.038) groups. There were no significant relations between marital status, family type, place of living and anxiety and depression risks (p0.05). Three quality of life parameters including general health, role limitations due to physical health and vitality scores in the inactive HBV carriers and CHB patients were lower than those of the control group (p0.05). Conclusions: Psychological state of the patients who are chronically infected with HBV should not be neglected during treatment and follow-up. If a psychiatric disturbance is identified, effective treatment will increase quality of life and improve compliance to treatment.
Açıklama
Anahtar Kelimeler
Hepatit B, Anksiyete, Depresyon, Yaşam kalitesi, Hepatitis B, Anxiety, Depression, Quality of life
Kaynak
Klimik Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
30
Sayı
3
Künye
Demir, L. S., Yiğit, Ö., Ural, O., Aktuğ Demir, N., Sümer, Ş., Güler, Ö. (2017). Kronik hepatit B hastaları ve inaktif hepatit B virusu taşıyıcılarında depresyon, anksiyete düzeyleri ve yaşam kalitesinin değerlendirilmesi. Klimik Dergisi, 30, 3, 136-141.
