The Effects of Steroid Therapy on Bone and Eyes in Children with Nephrotic Syndrome

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dc.contributor.authorAtaş, Bülent
dc.contributor.authorYüzüak, Serap Genç
dc.date.accessioned2020-01-18T21:02:57Z
dc.date.available2020-01-18T21:02:57Z
dc.date.issued2017
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Anabilim Dalıen_US
dc.description.abstractObjective: The aim of this study was to evaluate complications of long-term steroid usage on the eyes and bone metabolism, which can be detected at early stage, and to encourage the necessary precautions. Methods: This retrospective study was performed with data of patients who took steroid therapy for nephrotic syndrome and were followed up between June 2006-May 2011 at Necmettin Erbakan University. Results: Fifty-six patients were included in this study. The mean age of the patients was 4.22.3 years. The patients were examined in 3 groups according to steroid therapy. Group 1 was defined as patients who had not received steroids in the past year and who were in the remission stage, Group 2 comprised patients who had received steroids in the last year and who were in the remission stage, and Group 3 was made up of patients who were in the active nephrotic period and had received steroids. In terms of biochemical parameters (serum urea, creatinine, calcium, phosphorus, magnesium, alkaline phosphatase, parathyroid hormone, osteocalcin, vitamin D, triglycerides), there was no statistically significant difference between the 3 groups. Group 3 had a higher ratio of calcium/creatinine and protein/creatinine in spot urine than Groups 1 and 2. Of 56 patients, 40 patients had eye examinations. There was no statistically significant difference determined in terms of side effects of steroid treatment. Conclusion: Pediatricians should be very careful while following up the children who use steroids at a young age due to the possibility of cataract development and side effects on bone metabolism.en_US
dc.identifier.citationAtaş, B., Genç Yüzüak, S. (2017). The effects of steroid therapy on bone and eyes in children with nephrotic syndrome. Southern Clinics of Istanbul Eurasia, 28, 2, 93-98.
dc.identifier.endpage98en_US
dc.identifier.issn2587-0998en_US
dc.identifier.issn2587-1404en_US
dc.identifier.issue2en_US
dc.identifier.startpage93en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpjNU5ERTBOQT09/the-effects-of-steroid-therapy-on-bone-and-eyes-in-children-with-nephrotic-syndrome
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1385
dc.identifier.volume28en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofSouthern Clinics of Istanbul Eurasiaen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone mineral densityen_US
dc.subjectCorticosteroiden_US
dc.subjectNephrotic syndromeen_US
dc.subjectOcular complicationsen_US
dc.titleThe Effects of Steroid Therapy on Bone and Eyes in Children with Nephrotic Syndromeen_US
dc.typeArticleen_US

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