The prevalence of infectious agents in patients with systemic sclerosis

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dc.authoridRecep Keşli: :0000-0002-2622-0760
dc.contributor.authorBilgin, Hüseyin
dc.contributor.authorKocabaş, Hilal
dc.contributor.authorKeşli, Recep
dc.date.accessioned2020-01-18T21:02:51Z
dc.date.available2020-01-18T21:02:51Z
dc.date.issued2015
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Fizik Tedavi ve Rehabilitasyon Anabilim Dalıen_US
dc.descriptionWOS:000389053000049en_US
dc.descriptionPubMed ID:26775370en_US
dc.description.abstractBackground/aim: Systemic sclerosis (SSc) is an autoimmune disease characterized by microvascular injury, excessive extracellular matrix deposition, and fibrosis in the skin and internal organs. Bacterial and viral infectious agents have been suspected to be contributing factors in the development and progression of the pathologic features of SSc. Materials and methods: In this study, 30 SSc patients who were admitted to the rheumatology unit of the Konya Training and Research Hospital and 30 healthy controls were included. The presence of 9 different antibodies (IgM and IgG) against Helicobacter pylori, cytomegalovirus (CMV), EpsteinBarr virus (EBV), and parvovirus B19 were investigated in sera samples obtained from the 60 participants using an enzyme-linked immunosorbent assay method. The characteristics of current and past infections with H. pylori, CMV, EBV, and parvovirus B19 were evaluated by determining the seropositivity of the tested bacterial and viral agents. Results: The prevalences of H. pylori, CMV, EBV, and parvovirus B19 were determined to be higher in patients with SSc than in the control group. Conclusion: SSc is associated with a higher rate of certain infections, which deserves further investigation in order to assess the role of infections in disease etiology/pathogenesis.en_US
dc.identifier.citationKocabaş, H., Bilgin, H., Keşli, R. (2015). The prevalence of infectious agents in patients with systemic sclerosis. Turkish Journal of Medical Sciences, 45, 6, 1192-1197.en_US
dc.identifier.doi10.3906/sag-1404-150en_US
dc.identifier.endpage1197en_US
dc.identifier.issn1300-0144en_US
dc.identifier.issn1303-6165en_US
dc.identifier.issue6en_US
dc.identifier.pmid26775370en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1192en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TVRnMk5EUXlNZz09/the-prevalence-of-infectious-agents-in-patients-with-systemic-sclerosis
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1320
dc.identifier.volume45en_US
dc.identifier.wosWOS:000389053000049en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSystemic sclerosisen_US
dc.subjectİnfectionen_US
dc.subjectEtiologyen_US
dc.titleThe prevalence of infectious agents in patients with systemic sclerosisen_US
dc.typeArticleen_US

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