Assessment of Cardiovascular Parameters in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Disease

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dc.authorid0000-0002-2242-9401en_US
dc.contributor.authorEklioğlu, Beray Selver
dc.contributor.authorAtabek, Mehmet Emre
dc.contributor.authorAkyürek, Nesibe
dc.contributor.authorAlp, Hayrullah
dc.date.accessioned2020-01-18T21:02:58Z
dc.date.available2020-01-18T21:02:58Z
dc.date.issued2015
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalığı Anabilim Dalıen_US
dc.description.abstractObjective: The aim of this study was to evaluate the periaortic fat thickness (PAFT) using conventional echocardiography in obese children and adolescents with non-alcoholic fatty liver disease (NAFLD).Methods: Two hundred and ninety-seven obese children and adolescents were included in the study. Anthropometric measurements were made in all subjects, and fasting venous blood samples were taken for determination of glucose, insulin, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, triglycerides, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels. Ultrasonography of the liver was used for assessment of NAFLD and the subjects were grouped as NAFLD and non-NAFLD. Echocardiography was performed in all subjects.Results: PAFT was higher in patients with NAFLD compared with the nonNAFLD group. In patients with NAFLD, PAFT was positively correlated with waist circumference and with total cholesterol levels. In multiple regression analysis, waist circumference (?0.28, p>0.001) was found to be the best predictor of PAFT.Conclusion: Conventional echocardiography may be used to determine increased PAFT at an early stage in obese children and adolescents with NAFLD for careful monitoring of cardiovascular risken_US
dc.identifier.citationEklioğlu, B. S., Atabek, M. E., Akyürek, N., Alp, H. (2015). Assessment of Cardiovascular Parameters in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Disease. Journal of Clinical Research in Pediatric Endocrinology, 7, 3, 222-227.en_US
dc.identifier.doi10.4274/jcrpe.1949en_US
dc.identifier.endpage227en_US
dc.identifier.issn1308-5727en_US
dc.identifier.issn1308-5735en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage222en_US
dc.identifier.urihttp://app.trdizin.gov.tr/publication/paper/detail/TVRrNE9UWTBOQT09
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1386
dc.identifier.volume7en_US
dc.identifier.wosWOS:000360842500010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Clinical Research in Pediatric Endocrinologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEndokrinoloji ve Metabolizmaen_US
dc.subjectPediatrien_US
dc.subjectObesityen_US
dc.subjectNon-Alcoholic Fatty Liver Diseaseen_US
dc.subjectPeriaortic Fat Thicknessen_US
dc.subjectChildrenen_US
dc.subjectAdolescenten_US
dc.titleAssessment of Cardiovascular Parameters in Obese Children and Adolescents with Non-Alcoholic Fatty Liver Diseaseen_US
dc.typeArticleen_US

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