Effects of reproductive factors on bone mineral densitometry
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Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Postmenopozal kadınlarda reprodüktif faktörlerin kemik mineral yoğunluğu (BMD) üzerine etkilerini tespit etmek amaçlandı. Gereç ve Yöntemler: Çalışmaya lomber vertebra (L1-4) (LS) ve femur boyun (FN) düzeyinde BMD (gr/cm²) ölçümleri yapılmış olan 1196 postmenopazal kadın dahil edildi. Hastaların demografik, reprodüktif özellikleri ve vücut kütle indeksi (BMI) (kg/m²) belirlendi. BMD ile ilişkili faktörleri belirlemede çoklu regresyon analizi kullanıldı. Bulgular: Hastalarda ortalama yaş 59,978,56, ağırlık 73,4913,06 kg, VKİ 29,255,22 kg/m², adet yaşı 14,001,64, doğum sayısı 4,222,09, toplam emzirme süresi 60,7738,80 ay, günlük emzirme sayısı 8,233,91, menapoz yaşı 47,124,22, menopoz süresi 12,809,10 yıl, LS BMD 0,9930,171 gr/cm², FN BMD 0,8440,14 gr/cm² idi. Hastalarda LS BMD ve FN BMD değerleri ile yaş, menopoz süresi, toplam emzirme süresi, günlük emzirme sayısı arasında negatif korelasyon saptandı. LS ve FN BMD değerleri ile, ağırlık ve BMI skorları arasında pozitif korelasyon saptandı Yine LS ve FN BMD değerleri ile adet yaşı ve doğum sayısı arasında negatif korelasyon saptandı. Lineer basamak regresyon analizlerinde, ağırlık (p0,001), günlük emzirme sayısı (p0,001), menapoz sonrası geçen süre (p0,001), toplam emzirme süresi (p0,012), ilk adet yaşı (p0,007) LS BMD için, ağırlık (p0,001), menapoz sonrası geçen süre (p0,001) ve günlük emzirme sayısı (p0,001) FN BMD için en önemli belirleyiciler olarak bulundu. Sonuç: Postmenopozal dönemdeki kadınlarda LS ve FN BMD, reprodüktif faktörler ile ilişkili gözükmektedir. Bu nedenle postmenopozal kadınlarda osteoporoz risk faktörleri değerlendirirken reproduktif faktörlerde dikkate alınmalıdır. (Türk Os te opo roz Dergisi 2012;18:8-12)
Aim: To determine the effects of reproductive factors on bone mineral density (BMD) in postmenopausal women. Materials and Methods: A total of 1196 postmenopausal women with BMD (g/cm2) measurements at lumbar vertebra (LS) and femur neck (FN) were enrolled. Demographic, reproductive characteristics and Body Mass Index (BMI) of patients were defined. In order to define BMD related factors, multiple regression analysis was employed. Results: Main results were as follows: mean age 59.97±8.56 yrs; weight 73.49±13.06 kg; BMI 29.25±5.22kg/m², age of menarche 14.00±1.64 yrs; number of deliveries 4.22±2.09; total breastfeeding duration 60.77±38.80 months; number of breastfeeding per day 8.23±3.91; menopausal age 47.12±4.22 yrs; duration of menopause 12.80±9.10 yrs; LS BMD 0.993±0.171 gr/cm2; FN BMD 0.844±0.14 gr/cm2. There were negative correlations between LS BMD and FN BMD values and age, menopause duration, total breastfeeding duration, and number of breastfeeding per day. There were positive correlations between LS and FN BMD values, and weight and BMI scores. Additionally, there were negative correlations between LS and FN BMD values, and age of menarche and number of deliveries. In linear stage regression analysis, weight, number of breastfeeding per day, postmenopausal duration, duration of total breastfeeding and age of menarche were defined as the most significant predictors for LS BMD, whereas weight, postmenopausal duration and number of breastfeeding per day were defined as the most significant predictors for FN BMD. Conclusion: LS and FN BMD in postmenopausal women are related to reproductive factors, so reproductive factors should also be considered in the evaluation of risk factors in postmenopausal women. (Turkish Journal of Osteoporosis 2012;18:8-12)
Aim: To determine the effects of reproductive factors on bone mineral density (BMD) in postmenopausal women. Materials and Methods: A total of 1196 postmenopausal women with BMD (g/cm2) measurements at lumbar vertebra (LS) and femur neck (FN) were enrolled. Demographic, reproductive characteristics and Body Mass Index (BMI) of patients were defined. In order to define BMD related factors, multiple regression analysis was employed. Results: Main results were as follows: mean age 59.97±8.56 yrs; weight 73.49±13.06 kg; BMI 29.25±5.22kg/m², age of menarche 14.00±1.64 yrs; number of deliveries 4.22±2.09; total breastfeeding duration 60.77±38.80 months; number of breastfeeding per day 8.23±3.91; menopausal age 47.12±4.22 yrs; duration of menopause 12.80±9.10 yrs; LS BMD 0.993±0.171 gr/cm2; FN BMD 0.844±0.14 gr/cm2. There were negative correlations between LS BMD and FN BMD values and age, menopause duration, total breastfeeding duration, and number of breastfeeding per day. There were positive correlations between LS and FN BMD values, and weight and BMI scores. Additionally, there were negative correlations between LS and FN BMD values, and age of menarche and number of deliveries. In linear stage regression analysis, weight, number of breastfeeding per day, postmenopausal duration, duration of total breastfeeding and age of menarche were defined as the most significant predictors for LS BMD, whereas weight, postmenopausal duration and number of breastfeeding per day were defined as the most significant predictors for FN BMD. Conclusion: LS and FN BMD in postmenopausal women are related to reproductive factors, so reproductive factors should also be considered in the evaluation of risk factors in postmenopausal women. (Turkish Journal of Osteoporosis 2012;18:8-12)
Açıklama
Anahtar Kelimeler
Genel ve Dahili Tıp, Menopause, Bone Mineral Density, Reproductive Factors, Osteoporosis, Menopoz, Kemik Mineral Yoğunluğu, Reprodüktif Faktörler, Osteoporoz
Kaynak
Türk Osteoporoz Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
18
Sayı
1
Künye
Yılmaz, H., Erkin, G., Polat, H. A. D., Küçüksen, S., Sallı, A., Uğurlu, H. (2012). Effects of reproductive factors on bone mineral densitometry. Turk Osteoporoz Dergisi, 18, 1, 8-12.
