The effects of ankaferd blood stopper on DNA damage and enzymes with paranchymal damaged rabbits

Basit Öğe Kaydı
dc.authoridEsma Menevşe: 0000-0002-5477-5667
dc.authoridAbdullah Sivrikaya: 0000000329565681
dc.contributor.authorMetin, Bayram
dc.contributor.authorMenevşe, Esma
dc.contributor.authorSivrikaya, Abdullah
dc.contributor.authorAltınok, Tamer
dc.contributor.authorArıkoğlu, Hilal
dc.date.accessioned2020-01-18T21:02:50Z
dc.date.available2020-01-18T21:02:50Z
dc.date.issued2017
dc.departmentNEÜ, Meram Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Göğüs Cerrahisi Anabilim Dalıen_US
dc.description.abstractAnkaferd blood stopper (ABS) is a medical product that is used in several injuries, dental operations, prevention of minor or major bleeding after spontaneous or surgerical operations and have anti-microbial, anti-inflamatory, anti-thrombin, anti-platelet, anti-atherosclerotic, anti-oxidants effects. The present study is aimed to evaluate the effects of ABS on 8-hydroxy-2?-deoxyguanosine (8-OHdG), superoxide dismutase (SOD), myeloperoxidase (MPO) levels over pleural adhesions in rabbits with pulmonary parenchymal damage.16 New Zelland species rabbits were divided in two groups such as control (n7) and study group (n7). One rabbit in each group died during anesthesia. In both groups, we performed wedge resections in equal size to the left lower lobes of all rabbits. No interventions were made on control group, whereas 5 puff’s (1 cc) ABS was performed to the resection area at study group. Tube thoracostomy that performed both groups were terminated postoperatively at 6th hour after drainage and air leakages follow up. Rabbits were sacrificed with anesthetics at postoperative 8th day. Lung tissues were collected for analyzing of 8-OHdG, SOD, MPO. The 8-OHdG levels were respectively 2.010.39 ng/ml in control group and, 0.380.12 ng/ml in study. The differences between study and control group were statistically important group (p0.001). SOD and MPO levels did not show any statistically importance in the groups. As a conclusion, we can say that oxidative DNA damage prevented by ABS.en_US
dc.identifier.citationMetin, B., Menevşe, E., Sivrikaya, A., Altınok, T., Arıkoğlu, H. (2017). The effects of ankaferd blood stopper on DNA damage and enzymes with paranchymal damaged rabbits. Medicine Science, 6, 1, 5-10.
dc.identifier.endpage10en_US
dc.identifier.issn2147-0634en_US
dc.identifier.issn2147-0634en_US
dc.identifier.issue1en_US
dc.identifier.startpage5en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpZek56VTVPUT09/the-effects-of-ankaferd-blood-stopper-on-dna-damage-and-enzymes-with-paranchymal-damaged-rabbits
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1312
dc.identifier.volume6en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnkaferden_US
dc.subjectParanchyme damageen_US
dc.subject8-hydroxy-2ˈ-deoxyguanosinen_US
dc.subjectsuperoxide dismutaseen_US
dc.subjectmyeloperoxidaseen_US
dc.titleThe effects of ankaferd blood stopper on DNA damage and enzymes with paranchymal damaged rabbitsen_US
dc.typeArticleen_US

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