KDIGO (Kidney Disease: Improving Global Outcomes) Criteria As a Predictor of Hospital Mortality in Cirrhotic Patients

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dc.authorid0000-0001-8515-8760en_US
dc.authorid0000-0001-7332-686Xen_US
dc.contributor.authorBıyık, Murat
dc.contributor.authorAtaseven, Hüseyin
dc.contributor.authorBıyık, Zeynep
dc.contributor.authorAsil, Mehmet
dc.contributor.authorÇifçi, Sami
dc.contributor.authorSayın, Serhat
dc.contributor.authorDemir, Alien_US
dc.contributor.authorTombul, Halil Zekien_US
dc.date.accessioned2020-01-18T21:02:52Z
dc.date.available2020-01-18T21:02:52Z
dc.date.issued2016
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Anabilim Dalıen_US
dc.description.abstractBackground/Aims: Acute kidney injury (AKI) is frequent in cirrhotic patients and is associated with a poor prognosis. Recently, the Kidney Disease: Improving Global Outcomes (KDIGO) organization recommended new criteria for the diagnosis and staging for AKI. The aim of this study was to evaluate the presence of AKI according to KDIGO criteria in cirrhotic patients admitted to the hospital and to determine its association with hospital mortality.Materials and Methods: This retrospective study included 277 cirrhotic patients admitted to the intensive care unit and gastroenterology service of a tertiary referral hospital from January 2008 to January 2012. AKI was diagnosed and classified according to the KDIGO criteria.Results: The overall incidence of AKI in cirrhotic patients was 39%, and the overall hospital mortality was 15.5%. Patients without AKI had a hospital mortality rate of 2.4%, whereas the mortality rate for patients with AKI was 36.1%. The peak AKI stage detected during hospitalization was stage 1 for 58 patients (53.7%), stage 2 for 20 patients (18.5%), and stage 3 for 30 patients (27.7%). Mortality was found to be associated with the presence, stage, and progression of AKI. Multivariate analysis showed that AKI was an independent factor significantly associated with mortality (odds ratio: 9.1; 95% confidence interval: 2.89-29.1; p>0.001).Conclusion: KDIGO criteria can be used to evaluate AKI in cirrhotic patients. The prevalence of AKI in patients with cirrhosis is high, and AKI is associated with mortality. If early preventive measures are taken, it may be possible to prevent AKI progression and thus mortalityen_US
dc.identifier.citationBıyık, M., Ataseven, H., Bıyık, Z., Asil, M., Çifci, S., Sayın, S., Tonbul, H. Z., Demir, A. (2016). KDIGO (Kidney Disease: Improving Global Outcomes) criteria as a predictor of hospital mortality in cirrhotic patients. The Turkish Journal of Gastroenterology, 27, 2, 173-179.en_US
dc.identifier.doi10.5152/tjg.2016.15467en_US
dc.identifier.endpage179en_US
dc.identifier.issn1300-4948en_US
dc.identifier.issn2148-5607en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage173en_US
dc.identifier.urihttp://app.trdizin.gov.tr/publication/paper/detail/TVRrNU5UWXhNUT09
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1330
dc.identifier.volume27en_US
dc.identifier.wosWOS:000373402800013en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCerrahien_US
dc.subjectHospital Mortalityen_US
dc.subjectAcute Kidney İnjuryen_US
dc.subjectLiver Cirrhosisen_US
dc.titleKDIGO (Kidney Disease: Improving Global Outcomes) Criteria As a Predictor of Hospital Mortality in Cirrhotic Patientsen_US
dc.typeArticleen_US

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