Prognostic factors for survival in adult patients with grade II glial tumors

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dc.authoridGül Kanyılmaz: 0000-0003-2333-353X
dc.authoridMeryem Aktan: 0000-0002-0447-7784
dc.contributor.authorKanyılmaz, Gül
dc.contributor.authorAktan, Meryem
dc.contributor.authorKarahacıoğlu, Eray
dc.contributor.authorÖnder, Hatice
dc.date.accessioned2020-01-18T21:03:17Z
dc.date.available2020-01-18T21:03:17Z
dc.date.issued2018
dc.departmentNEÜ, Meram Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Radyasyon Onkolojisi Anabilim Dalıen_US
dc.description.abstractAim: To investigate survival results of patients with low grade gliomas (LGGs) and to evaluate the predictive role of clinico-pathologic prognostic factors on survival. Material and Methods: Between 2003 and 2014, the adult patients with Grade II glial tumors were evaluated retrospectively. Several variables were investigated to find prognostic factors related with the overall survival (OS) and progression-free survival (PFS). Results: This study involved in 124 patients with median 40 (range; 6-132) months follow up. The average OS for the all patients was 7.8 years. 2-, 5- and 10- year OS ratios were 91%, 73% and 55%, respectively. Patients with low pignatti risk score had a longer OS than high pignatti risk score (p=0.01). Patients with seizure had a better OS (p=0.03). Patients with biopsy/partial resection had apoorer OS (p=0.02). Patients with residue after initial surgery had a worse OS (p=0.03). If the patients had recurrence or progression, the patients had poorer OS (p=0.01). Tumor with malignant transformation (p=0.01) and glioblastoma subtype after second surgery (p=0.003) had a poorer OS. The Pignatti risk score and seizure were the independent prognostic factors for PFS. Conclusion: The extent of surgery and recurrence or progression of Grade II glioma were the independent prognostic factors for OS. The Pignatti risk score and seizure were the independent prognostic factors for PFS.en_US
dc.identifier.citationKanyılmaz, G., Aktan, M., Karahacıoğlu, E., Önder, H. (2018). Prognostic factors for survival in adult patients with grade II glial tumors. İnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisi, 25, 1, 105-111.
dc.identifier.doi10.5455/jtomc.2017.12.151en_US
dc.identifier.endpage111en_US
dc.identifier.issn1300-1744en_US
dc.identifier.issue1en_US
dc.identifier.startpage105en_US
dc.identifier.urihttps://dx.doi.org/10.5455/jtomc.2017.12.151
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpnMU5EQTJOZz09/prognostic-factors-for-survival-in-adult-patients-with-grade-ii-glial-tumors
dc.identifier.urihttps://hdl.handle.net/20.500.12452/1519
dc.identifier.volume25en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofİnönü Üniversitesi Turgut Özal Tıp Merkezi Dergisien_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US]
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGrade II gliomaen_US
dc.subjectPrognostic factorsen_US
dc.subjectProgression or Recurrence Free Survivalen_US
dc.subjectRadiotherapyen_US
dc.subjectSurvivalen_US
dc.titlePrognostic factors for survival in adult patients with grade II glial tumorsen_US
dc.typeArticleen_US

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