Osteoporozda Yaşam Kalitesi: Bir Kontrollü Çalışma
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Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Bu çalışmada vertebral veya non-vertebral kırığı olmayan postmenopozal osteoporozlu (PMO), osteopenik ve normal kemik mineral yoğunluğuna (KMY) sahip kadınların yaşam kalitesini değerlendirmek ve yaşam kalitesi üzerine etkili faktörleri belirlemek amaçlandı. Gereç ve Yöntemler: Kırığı olmayan PMO’lu 266 kadın, 310 osteopenik kadın ve 255 normal KMY’li kadın çalışmaya alındı. KMY ölçümü, dual enerji X-ray absorbsiyometri (DXA) ile lomber vertebra (L1-4) ve femur boyundan yapıldı. Yaşam kalitesi Avrupa Osteoporoz Kurumu Yaşam Kalitesi Anketi (QUALEFFO) kullanılarak değerlendirildi. Grupların QUALEFFO total skorları ve alt grup skorları karşılaştırıldı. Korelasyon analizi ile PMO’lu kadınlarda yaşam kalitesi ile ilişkili faktörler belirlendi. Yaşam kalitesi ile en yüksek korelasyona sahip değişkenler lineer regresyon modeline alındı. Bulgular: Kırığı olmayan PMO’lu kadınlarda QUALEFFO total skor ve alt grup skorları osteopenik ve normal KMY’e sahip gruba göre anlamlı derecede yüksekti. PMO’lu kadınlarda QUALEFFO total skoru ile yaş, vücut kitle indeksi (VKİ), doğum sayısı ve menapoz süresi arasında pozitif korelasyon, eğitim düzeyi, gelir düzeyi, femur boyun KMY skorları arasında negatif korelasyon tespit edildi. Lineer regresyon analizi sonucunda, yaşam kalitesinin en önemli belirleyicileri olarak VKİ, femur boyun KMY, doğum sayısı ve menapoz süresi tespit edildi. Sonuç: Bu çalışmanın sonuçları kırığı olmayan PMO’lu kadınların yaşam kalitelerinin osteopenik ve normal KMY’ye sahip kadınlara göre belirgin derecede bozulduğunu ve yaşam kalitesinin birçok faktörden etkilendiğini göstermektedir. (Türk Osteoporoz Dergisi 2012;18: 47-52)
Aim: To evaluate quality of life in women without vertebral and nonvertebral fractures, with postmenopausal osteoporosis (PMO), osteopenic and normal bone mineral density (BMD), and to determine effective factors on quality of life. Materials and Methods: Without fractures, 266 women with PMO, 310 with osteopenia and 255 with normal women BMD were enrolled in the study. BMD measurement was performed on lumbar vertebra (L1-L4) and femur neck via dual energy X-ray absorbtiometry (DXA). Quality of life was assessed with Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). QUALEFFO total scores and subscales were compared in all groups. Factors about quality of life in women with PMO were defined with correlation analysis. Variations of the highest correlation and quality of life were included into linear regression model. Results: In non-fractured women with PMO, QUALEFFO total scores and subscales were higher than those with osteopenia and normal BMD. In women with PMO, a positive correlation was found between QUALEFFO total scores, and age, Body Mass İndex (BMI), parity and duration of menopause, and a negative correlation between QUALEFFO total scores, and level of education, economical status and femur neck BMD scores. In linear regression analysis, among significant factors of quality of life were BMI, femur neck BMD, parity and duration of menopause. Conclusion: Our results indicate that quality of life in non-fractured women with PMO is disordered higher than those with osteopenia and normal BMD, and quality of life are affected by numerous factors. (Turkish Journal of Osteoporosis 2012;18: 47-52)
Aim: To evaluate quality of life in women without vertebral and nonvertebral fractures, with postmenopausal osteoporosis (PMO), osteopenic and normal bone mineral density (BMD), and to determine effective factors on quality of life. Materials and Methods: Without fractures, 266 women with PMO, 310 with osteopenia and 255 with normal women BMD were enrolled in the study. BMD measurement was performed on lumbar vertebra (L1-L4) and femur neck via dual energy X-ray absorbtiometry (DXA). Quality of life was assessed with Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO). QUALEFFO total scores and subscales were compared in all groups. Factors about quality of life in women with PMO were defined with correlation analysis. Variations of the highest correlation and quality of life were included into linear regression model. Results: In non-fractured women with PMO, QUALEFFO total scores and subscales were higher than those with osteopenia and normal BMD. In women with PMO, a positive correlation was found between QUALEFFO total scores, and age, Body Mass İndex (BMI), parity and duration of menopause, and a negative correlation between QUALEFFO total scores, and level of education, economical status and femur neck BMD scores. In linear regression analysis, among significant factors of quality of life were BMI, femur neck BMD, parity and duration of menopause. Conclusion: Our results indicate that quality of life in non-fractured women with PMO is disordered higher than those with osteopenia and normal BMD, and quality of life are affected by numerous factors. (Turkish Journal of Osteoporosis 2012;18: 47-52)
Açıklama
Anahtar Kelimeler
Postmenopozal osteoporoz, Yaşam kalitesi, Kemik mineral yoğunluğu, QUALEFFO, Postmenopausal osteoporosis, Quality of life, Bone mineral density
Kaynak
Türk Osteoporoz Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
18
Sayı
2
Künye
Küçükşen, S., Uğurlu, H., Yılmaz, H., Erkin, G., Demir Polat, H. A., Sallı, A. (2012). Osteoporozda yaşam kalitesi: Bir kontrollü çalışma. Türk Osteoporoz Dergisi, 18, 2, 47-52.
