Evaluation of pre- and postoperative corrected QT dispersion predicting the development of arrhythmias in children undergoing congenital heart surgery
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Dosyalar
Tarih
2012
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Çalışmada doğuştan kalp cerrahisi yapılan çocuklarda ameliyat öncesi ve sonrası QTc dispersiyonu değişkenliği
değerlendirildi.
Çalışma planı: Ekim 2006 - Mart 2011 tarihleri arasında doğuştan kalp cerrahisi yapılan ve ilk dahil edilme kriterlerini karşılayan ardışık 279 hasta (144 kadın, 135 erkek; ort. yaş 56.6±5.0 ay;
dağılım 15 gün-17 yaş) çalışmaya alındı. QTc dispersiyon ölçümleri, hastalardan ameliyat öncesi (bir ay) ve ameliyat sonrası (bir
hafta) dönemde elde edilen standart 12 derivasyonlu istirahat
elektrokardiyogramlarından hesaplandı.
Bulgular: Kardiyak cerrahi yapılan tüm hastaların %75.9’unda
QTc dispersiyonu, ameliyat sonrası ameliyat öncesinden istatistiksel olarak yüksek bulundu. Çalışma grubunda en
sık tespit edilen doğuştan kalp hastalıkları ventriküler septal
defekt (VSD) ve sekundum atriyal septal defekt (ASD) idi. Ventriküler septal defekt, atriyoventriküler septal
defekt, Fallot tetrolojisi (TOF) ve sekundum ASD onarımları QTc dispersiyonundaki artış için majör risk faktörleriydi.
Ancak, VSD ile pulmoner stenoz onarımı, koarktasyonda aortun uç uca anostomozu, patent duktus arteriozus ligasyonu ve
divizyonu, pulmoner bant ve Glenn prosedürü yapılan çocuklarda ameliyat öncesi ve sonrası QTc dispersiyonları arasında
istatistiksel fark bulunmadı. Yapılan kardiyak ameliyatın tipine
göre ortaya çıkan aritmiler, uzun QTc dispersiyonu olan grupta,
olmayanlara kıyasla, istatistiksel olarak yüksekti.
Sonuç: QTc dispersiyonu ölçümü aritmilerin araştırılmasında
kullanışlı ve invaziv olmayan bir elektrokardiyografik testtir. Çalışma sonuçları, QTc dispersiyonunun ameliyat sonrası
dönemde kullanımının ortaya çıkacak aritmilerin öngörüsünde
yardımcı olabileceğini göstermektedir.
Background: The aim of this study was to evaluate pre- and postoperative QTc dispersion variability in children undergoing congenital cardiac surgery. Methods: Between October 2006 and March 2011, 279 consecutive patients (144 females, 135 males; mean age 56.6±5.0 months; range 15 days to 17 years) who met initial inclusion criteria and underwent congenital cardiac surgery were included. QTc dispersion measurements were calculated based on the standard 12-lead resting electrocardiograms of the patients in the preoperative (one month) and postoperative (one week) period. Results:In 75.9% of all patients with cardiac surgery, postoperative QTc dispersion was statistically higher from preoperative QTc dispersion. Ventricular septal defect (VSD) and secundum atrial septal defect (ASD) were the most common congenital heart diseases in the study population. Repair of VSD, atrioventricular septal defect, tetralogy of Fallot, (TOF) and secundum ASD were the major risk factors for increased QTc dispersion. However, no statistical difference was found between pre- and postoperative QTc dispersion in children who underwent repair of VSD and pulmonary stenosis, end-toend anastomosis of aorta for coarctation, patent ductus arteriosus ligation and division, pulmonary banding, and Glenn procedure. The occurrence of arrhythmia in prolonged QTc dispersions according to the type of cardiac surgery was statistically higher from those without prolonged QTc dispersion. Conclusion: QTc dispersion measurement is a useful noninvasive electrocardiographic test in the evaluation of arrhythmias. The study results suggest that use of QTc dispersion in the postoperative period may be helpful in the prediction of the development of arrhythmias.
Background: The aim of this study was to evaluate pre- and postoperative QTc dispersion variability in children undergoing congenital cardiac surgery. Methods: Between October 2006 and March 2011, 279 consecutive patients (144 females, 135 males; mean age 56.6±5.0 months; range 15 days to 17 years) who met initial inclusion criteria and underwent congenital cardiac surgery were included. QTc dispersion measurements were calculated based on the standard 12-lead resting electrocardiograms of the patients in the preoperative (one month) and postoperative (one week) period. Results:In 75.9% of all patients with cardiac surgery, postoperative QTc dispersion was statistically higher from preoperative QTc dispersion. Ventricular septal defect (VSD) and secundum atrial septal defect (ASD) were the most common congenital heart diseases in the study population. Repair of VSD, atrioventricular septal defect, tetralogy of Fallot, (TOF) and secundum ASD were the major risk factors for increased QTc dispersion. However, no statistical difference was found between pre- and postoperative QTc dispersion in children who underwent repair of VSD and pulmonary stenosis, end-toend anastomosis of aorta for coarctation, patent ductus arteriosus ligation and division, pulmonary banding, and Glenn procedure. The occurrence of arrhythmia in prolonged QTc dispersions according to the type of cardiac surgery was statistically higher from those without prolonged QTc dispersion. Conclusion: QTc dispersion measurement is a useful noninvasive electrocardiographic test in the evaluation of arrhythmias. The study results suggest that use of QTc dispersion in the postoperative period may be helpful in the prediction of the development of arrhythmias.
Açıklama
WOS:000310402100005
Anahtar Kelimeler
Cardiac arrhythmias, Children, Congenital heart surgery, Qtc dispersion, Kardiyak aritmiler, Çocuklar, Doğuştan kalp cerrahisi, Qtc dispersiyonu
Kaynak
Türk Göğüs Kalp Damar Cerrahisi Dergisi
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
20
Sayı
4
Künye
Alp, H., Baysal, T., Narin, C., Sarıgül, A. (2012). Evaluation of pre- and postoperative corrected QT dispersion predicting the development of arrhythmias in children undergoing congenital heart surgery. Turkish Journal of Thoracic and Cardiovascular Surgery, 20, 4, 716-721.
