Yazar "Uyar, Mehmet" seçeneğine göre listele
Listeleniyor 1 - 20 / 28
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Antioxidant effects of bisphosphonates in smoking- induced lung injury in rat model(European Respiratory Soc Journals Ltd, 2015) Korkmaz, Celalettin; Yavsan, Durdu Mehmet; Demirbas, Soner; Oltulu, Pembe; Kilinc, Ibrahim; Uyar, Mehmet; Gok, Mehmet[Abstract Not Availabe]Öğe Assessment of abdominal aortic calcification at different stages of chronic kidney disease(Springer, 2016) Biyik, Zeynep; Selcuk, Nedim Yilmaz; Tonbul, Halil Zeki; Anil, Melih; Uyar, MehmetVascular calcifications that may cause cardiovascular disease are highly prevalent in chronic kidney disease (CKD). In this study, we aimed to determine abdominal aorta calcifications (AAC) in predialysis and hemodialysis patients by lateral lumbar radiography and to investigate factors that were associated with the calcifications. Two hundred and fifty-nine adult chronic hemodialysis patients, 300 predialysis CKD patients and 60 healthy subjects with normal kidney function as a control group were enrolled in the study. Lateral lumbar radiography was used to measure AAC. Calcified deposits of the abdominal aorta wall at the level of the first through fourth lumbar vertebrae were graded by a 24-point scoring system. AAC prevalence (AAC score aeyen1) was significantly different in hemodialysis, predialysis and control groups (71.8, 45.7 and 33.3 %, respectively; p < 0.001). AAC prevalence in CKD stages 1, 2, 3, 4 and 5 predialysis patients was 26.6, 43.3, 40, 58.3 and 55 %, respectively. AAC scores of the hemodialysis group were higher than of the predialysis group (p < 0.001) and the control group (p < 0.001). AAC scores of the predialysis group were not higher than of the control group (p = 0.314). AAC scores of the hemodialysis group were significantly higher than of the control group (p < 0.001) and stage 1 (p < 0.001), stage 2 (p = 0.001) and stage 3 predialysis groups (p = 0.002). Age (p < 0.001), presence of diabetes mellitus (p < 0.001) and serum phosphorus levels (p = 0.011) were found to be independent predictors of calcification in the hemodialysis group. Age (p < 0.001), serum phosphorus levels (p = 0.007) and history of cardiovascular disease (p = 0.014) were found to be independent predictors of calcification in the predialysis group. Abdominal aortic calcification is highly prevalent in the hemodialysis population. Strict phosphorus control should be implemented to the predialysis and hemodialysis patients.Öğe Association between Red Blood Cell Distribution Width and Acute Pancreatitis(Int Scientific Information, Inc, 2014) Karabulut, Keziban Ucar; Narci, Huseyin; Ucar, Yildiz; Uyar, MehmetBackground: We aimed to determine whether there are any alterations in red blood cell width in patients diagnosed with acute pancreatitis. Material/Methods: This was a retrospective study of records of patients treated in emergency units and diagnosed with acute pancreatitis between January 2011 and April 2013. Records were investigated regarding patient age, sex, and causes of acute pancreatitis. Red blood cell width and amylase values obtained from the patients during diagnosis and after a full recovery from acute pancreatitis were added to the records. Results: Recorded red blood cell width and amylase values of 104 patients diagnosed with acute pancreatitis were statistically compared according to the time of sample collection. Samples were collected in the post-diagnostic period and after full recovery. Values of red blood cell width and amylase were found to be significantly higher in samples collected during hospital admission in comparison to those obtained from patients after fully recovering from acute pancreatitis (p<0.05). Conclusions: An increase in red blood cell width value is a marker of acute pancreatitis; therefore, we suggest that red blood cell width can be used as a tool for the early diagnosis and assessment of disease progression.Öğe The change of neutrophils/lymphocytes ratio in migraine attacks: A case-controlled study(Elsevier Sci Ltd, 2016) Karabulut, Keziban Ucar; Egercioglu, Tomris Ugur; Uyar, Mehmet; Ucar, YildizObjective: As commonly seen symptoms, headaches are among the most frequently encountered health challenges in emergency rooms by healthcare professionals. Among one of the most commonly seen and primary headaches is migraine. Migraines are mostly accompanied by functional deficits. Aims: To observe the changes of neutrophil/lymphocyte ratio occurring during migraine attacks. Method: This is a retrospective study where hospital records of patients previously diagnosed with migraine and admitted to the emergency with the complaints of attacks between May 2014 and January 2015 were investigated. All patients in the study were evaluated as to age, gender and complete blood count. Additionally, a healthy control group was formed with individuals with no disorders. By also evaluating the same features in the controls, the values found in the patients and controls alike were compared. Results: The values of white blood cell, lymphocyte, neutrophil, hemoglobin, thrombocyte and neutrophil/lymphocyte ratio determined in the patient group (n = 92) were statistically compared with those of the controls (n = 67). Neutrophil/lymphocyte ratio during the attacks was found higher in the patients, compared to the controls. Conclusion: Neutrophil/lymphocyte ratio is a sign of inflammation, and we consider that this ratio will also increase during migraine attacks, as with other inflammatory and acute processes. (C) 2016 The Authors. Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd.Öğe Conjunctival Flora in Diabetic and Nondiabetic Individuals(Turkish Ophthalmological Soc, 2015) Adam, Mehmet; Balci, Mehmet; Bayhan, Hasan Ali; Inkaya, Ahmet Cagkan; Uyar, Mehmet; Gurdal, CananObjectives: To evaluate the conjunctival bacterial flora in diabetic patients and nondiabetic subjects. Materials and Methods: Fifty-three diabetic patients and 43 nondiabetic healthy individuals were included in the study. A specimen was taken from each participant for the study by rubbing a sterile cotton-tipped swab on the inferior palpebral conjunctiva of the right eye. Samples were incubated in blood agar, chocolate agar, eosin methylene-blue lactose sucrose agar and sabouraud 4% dextrose agar. Isolated microorganisms were identified using routine microbiological methods. Results: Rates for bacterial isolations were determined as 38.5% in diabetic patients and 34.9% in nondiabetic controls. Staphylococcus aureus was isolated in 30% of cases in the diabetic patient group, while 20% tested positive for Escherichia call, 10% for coagulase-negative Staphylococcus, 10% for Klebsiella pneumoniae and 30% for multiple bacteria. In the non-diabetic group, 53.3% of patients were positive for Staphylococcus aureus while coagulase-negative Staphylococcus was isolated in 26.7%, Klebsiella pneumoniae in 6.7% and multiple bacteria in 13.3% of patients. Although there was no statistically significant difference in the number of isolated bacteria between the diabetic and nondiabetic groups, gram-negative bacterial colonization was significantly higher in diabetic patients (chi(2) = 0.129, p=0.719 and chi(2)=5.60, p = 0.018, respectively). Conclusion: Gram-negative bacteria are more common in the conjunctival flora of diabetic patients. This should be considered by clinicians when treating ocular infections in diabetic patients.Öğe Determination of the Knowledge, Attitudes and Behaviors of Adults At and Over the Age of 18 On Vaccines and Vaccination(Bilimsel Tip Yayinevi, 2019) Uyar, Mehmet; Yildirim, Elif Nur; Sahin, Tahir KemalIntroduction: The aim of this study was to determine the knowledge, attitudes and behaviors of adults aged 18 years and older about vaccines and vaccination and to establish vaccine hesitancy and vaccine rejection rates in the population. Materials and Methods: This cross-sectional study was conducted in five primary care clinics in Meram, Konya. The sample size of the study was 130. Between 10 and 31 October 2018, 134 subjects aged 18 and over who applied to the primary care clinics for any reason were included into the study. For the research, a data collection form consisting of 23 questions was developed by the researchers. The data collection form was applied to the participants by face-to-face interview method. Data entry, statistical analysis and report writing were done with computer. In summarizing numerical data, arithmetic mean, standard deviation, minimum and maximum values were used, and in summarizing categorical data, frequencies and percentages were used. Results: 52.2% of the participants were females, 59% were married and 35.1% were high school graduates. 79.9% of the volunteers knew at least one vaccine-protected disease, 44.8% of them knew at least one vaccine in the vaccination chart and 16.4% of them knew at least one vaccine not included in the vaccination chart. 93.9% of the participants thought that vaccination is necessary. 65.3% of the participants learned about vaccines from health care workers. There was no one who refused all vaccinations among the people involved in the research. We found that 9% of the study group had vaccine hesitancy. 84% of the respondents stated that they would like to vaccinate themselves and their children if the vaccine was produced in our country. Conclusion: As a result of the study, it was found that the participants had a positive attitude about vaccines and vaccination. No vaccine rejection was observed in our study group, but it was found that there was a 9% vaccine hesitation. There was a high-level support in the participants for the production and use of native Turkish vaccines.Öğe Development of a knowledge scale for cancer screening(Springer Heidelberg, 2023) Yildirim-Ozturk, Elif Nur; Uyar, MehmetBackgroundCancer screening is an important component in the struggle against cancer-induced morbidity and mortality. The aim of the study was to develop a scale that will measure the knowledge about cancer screening and will be used in the Turkish society.MethodsThe research is a scale development (validity and reliability) study. A total of 265 men and women between the ages of 18-70 are included in the study. The data collection form used in the study comprises two parts. It is a 15-item questionnaire on sociodemographic characteristics form and a candidate scale with 28 items.ResultsThe mean age of the participants was 41 years; 50.9% (n=135) were female. The face and content validity of the scale were done by two different teams. Item score-scale score correlation <0.20 in 1 item out of 28 items. During the structural factor analysis, 2 items with a factor load of ConclusionAs a result of the research, a new scale called 'Knowledge Scale for Cancer Screening' is developed, comprising 25 items and 3 sub-dimensions.Öğe Development of an Attitude Scale for Cancer Screening(Kare Publ, 2020) Ozturk, Elif Nur Yildirim; Uyar, Mehmet; Sahin, Tahir KemalOBJECTIVE This study aims to develop a scale to measure people's attitudes towards cancer screening and conduct a pilot study and validity-reliability study of the developed scale. METHODS This methodological study was conducted on 334 voluntary male and female relatives of patient who were between 30-70 years of age and attend family health centers at Meram district of Konya province. A sociodemographic form and a candidate scale were used for data collection. Data analysis was performed in a computer setting. RESULTS The study group of 334 participants consisted of 50% males and 50% females, and the mean age was 42.93 +/- 9.60 years. Four items with item score-scale score correlation less than +/- 0.200 were excluded from the 28-item candidate scale. Cronbach's alpha coefficient of the 24-item scale was calculated as 0.95. Face and content validity of the scale was evaluated with two different groups. Factor analysis that was used to assess the construct validity of the one-dimensional 24-item scale determined that explained the variance ratio was 52.62%. CONCLUSION As a result of our study, a new five-point Likert scale called Attitude Scale for Cancer Screening has been developed. Validity and reliability studies of the scale suggest that the scale is suitable for use in our society.Öğe Diabetik hastalarda bel ve boyun çevresi ölçümü ile glukoz, lipid ve HBA1C parametreleri arasındaki ilişki(2015) Turan, Elif; Savut, Bülent; Kulaksızoğlu, Mustafa; Uyar, Mehmet; Turan, Yaşar; Kaya, AhmetAmaç: Diyabet olan hastalarda bel çevresi ve boyun çevresinin; glukoz, HBA1c lipid parametreleri ve kan basıncı üzerine etkisini tespit etmek. Gereç ve Yöntemler: Necmettin Erbakan Üniversitesi Meram Tıp Fakültesi Endokrinoloji Kliniğine son 6 ayda başvuran 264 Tip 2 Diabetes Mellitus tanısı olan hasta çalışmaya dahil edildi. Bu hastaların kan basıncı, boy, kilo, bel çevresi ve boyun çevresi (BÇ) ölçüldü. Ölçüm sonuçları ile açlık plazma glukoz (APG), A1c lipid para- metreleri ve kan basıncı arasında verilerin korelasyonuna bakıldı. Bulgular: Çalışmaya alınan 264 hastanın 141i (%53.4) kadın, 123i (%46.6) erkekti. Hastaların ortalama yaş 55.7 10, VKİ 31.1 5.5 kg/m2, A1c %8.72.4, APG 18182 mg/dL, trigliserit 182111.7 mg/dL, HDL 42.911.7 mg/dL, LDL 111.834 mg/dL, sistolik kan basıncı (SKB) 13120 mmHg, diastolik kan basıncı (DKB) 81.612 mmHg, kadında bel çevresi ortalama 10614 cm, BÇ 36.22.8 cm, erkekte bel çevresi ortalama 105.912.8 cm, BÇ 37.95.1 cm olarak ölçüldü. Kadınlarda ve erkeklerde ayrı ayrı analizde BKİ ile bel çevresi, BÇ, SKB, DKB arasında anlamlı pozitif korelasyon bulundu (her biri için p0.001). Hem kadında hem erkekte boyun çevresi ile SKB, DKB trigliseritte pozitif korelasyon (sırasıyla p0.001, p0.001, p0.02) tespit edilirken, boyun çevresi ve HDL arasında negatif yönde korelasyon bulundu (p0.09). Kadın ve erkekler diyabetik hastalarda bel çevresi ile SKB ve DKB arasında pozitif korelasyon varken (sırasıyla p0.001, p0.001) ve HDL arasında negatif yönde korelasyon tespit edildi (p0.049). Bel çevresi ve boyun çevresi A1C, APG ve LDL-kolesterol arasında korelasyon tespit edilmedi. Sonuç: Bel çevresinin yanında boyun çevresi ölçümü takibi diyabetik hastalarda metabolik değişiklikleri yan- sıtan önemli ve basit fizik muayene bulgusu olarak kullanılabilir.Öğe Diyabetik ve Diyabetik Olmayan Bireylerde Konjunktiva Florası(2015) Adam, Mehmet; Balcı, Mehmet; Bayhan, Hasan Ali; İnkaya, Ahmet Çağkan; Uyar, Mehmet; Gürdal, CananAmaç: Diyabetik ve diyabetik olmayan olgularda konjunktival bakteri florasının incelenmesidir.Gereç ve Yöntem: Elli üç diyabetik hasta ve 43 diyabetik olmayan sağlıklı kişi çalışmaya dahil edildi. Çalışma için katılımcıların sağ göz alt fornikslerinden steril eküvyonla sürüntü alındı. Örnekler mikrobiyoloji laboratuvarında kanlı agar, çikolata agar, eosin metilen mavisi laktoz sukroz agar ve sabouraud %4 dekstroz agara ekildi. İzole edilen mikroorganizmalar rutin mikrobiyolojik yöntemlerle tanımlandı.Bulgular: Bakteri izolasyon oranı diyabetik hastalarda %38,5 ve diyabetik olmayanlarda %34,9 idi. Diyabetik grupta olguların %30'unda Staphylococcus aureus, %20'sinde Escherichia coli, %10'unda koagülaz negatif Staphylococcus, %10'unda Klebsiella pneumoniae ve %30'unda birden fazla bakteri üremesi saptandı. Diyabetik olmayan grupta %53,3'ünde Staphylococcus aureus, %26,7'sinde koagülaz negatif Staphylococcus, %6,7'sinde Klebsiella pneumoniae ve %13,3'ünde birden fazla bakteri üremesi gözlendi. Her iki grupta izole edilen bakterilerin sayısında istatistiki fark bulunmazken, diyabetik olgularda gram-negatif bakteri kolonizasyonu daha yüksekti (sırasıyla ?20,129, p0,719 ve ?25,60, p0,018).Sonuç: Gram-negatif bakteriler diyabetik hastaların konjunktiva florasında daha sık olarak bulunmaktadır. Bu durum diyabetik hastalarda göz enfeksiyonlarını tedavi ederken dikkate alınmalıdır.Öğe Effect of cineole, alpha-pinene, and camphor on survivability of skin flaps(Tubitak Scientific & Technological Research Council Turkey, 2018) Ince, Bilsev; Dadaci, Mehmet; Kilinc, Ibrahim; Oltulu, Pembe; Yarar, Serhat; Uyar, MehmetBackground/aim: The aim of this study was to determine the specific component of Rosmarinus officinalis (RO) responsible for increased flap survival and how RO displays its efficacy. Materials and methods: Rectangular random-pattern flaps were elevated from the back of each rat. Group I was the control group. In group II 0.1 mL of cineole, in group III 0.1 mL of alpha-pinene, in group IV 0.1 mL of camphor, in group V 0.1 mL each of alpha-pinene and cineole, in group VI 0.1 mL each of alpha-pinene and camphor, in group VII 0.1 mL each of cineole and camphor, and in group VIII, 0.1 mL each of alpha-pinene, cineole, and camphor was orally administered once a day before surgery. The luminal area of the largest blood vessel in the proximal flap was measured. Interleukin-1, tumor necrosis factor alpha, thiobarbituric acid reactive substances, and vascular endothelial growth factor values were measured. Results: The mean percentage of the viable surface area was significantly greater in groups VIII, III, and V. The mean percentage of vessel diameter was significantly greater in groups V, VIII, and VII. Conclusion: We suggest that alpha-pinene and cineole were the components of RO that were responsible for increased flap survival. The most effective of feature of RO was the antiinflammatory effects.Öğe The effect of rs9939609 FTO gene polymorphism on weight loss after laparoscopic sleeve gastrectomy(Springer, 2016) Balasar, Ozgur; Cakir, Tugrul; Erkal, Ozgur; Aslaner, Arif; Cekic, Bulent; Uyar, Mehmet; Bulbuller, NurullahPurpose Remarkable differences in weight loss have been observed in obese patients undergoing laparoscopic sleeve gastrectomy (LSG). These high variations might be partly explained by genetic factors. The rs9939609 fat mass and obesity-associated gene (FTO) polymorphism has been implicated in the susceptibility of obesity. We aimed to explore the effects of the rs9939609 FTO gene polymorphism on weight loss among severely obese patients applying for LSG. Materials and methods All individuals were analyzed for the FTO rs9939609 gene polymorphism. A total of 74 morbid obese patients (20 male, 54 female) were operated. Body weight and body mass index (BMI) were measured at before LSG and after surgery at the sixth month. Results Twenty-eight patients (37.8 %) had genotype TT (wild-type allel), 36 patients (48.6 %) had genotype TA, and 10 patients (13.5 %) had genotype AA. In both wildtype group and mutant group, BMI and weight levels decreased at the sixth month after surgery. Percent of excess weight loss (EWL) at 6 months of follow-up was similar in both groups. There were no differences between the mutant and wild-type groups percent of EWL at the sixth month after applying LSG. Conclusion Our data showed that the rs9939609 FTO gene polymorphism is not a useful genetic test prior to LSG to help clinicians predicting the weight loss for severely obese patients in short-term follow-up.Öğe The effect of smoking on the psoriasis: Is it related to nail involvement?(Wiley, 2020) Temiz, Selami Aykut; ozer, Ilkay; Ataseven, Arzu; Dursun, Recep; Uyar, MehmetPsoriasis is a chronic inflammatory skin disease that negatively affects the quality of life with remissions and relapses. Smoking, which is known to accelerate the development of comorbidities that can accompany psoriasis such as atherosclerotic heart disease, metabolic syndrome, is also an independent risk factor for psoriasis. In our study, we aimed to investigate the relationship between smoking and psoriasis. The study included a total of 476 participants with 276 psoriasis patients and 200 healthy volunteers. One hundred and thirty-nine (69.5%) cases in the psoriasis group and 61 (30.5%) cases in the control group were smoking. Patients with psoriasis had more cigarette smoking than the control group (P < .001). Smoking was present in 100 cases (61%) of 164 cases with nail psoriasis and psoriatic nail was significantly more frequently observed in patients with psoriasis when smoking was present (P < .001). It was observed that systemic treatment requirements were higher in smoking psoriasis patients (P= .04). It is known that cigarette use increases in patients with psoriasis compared to the normal population, and cigarette use also increases the psoriasis area severity index (PASI). In our study, a significant relationship was found between smoking and psoriasis nail involvement first in the literature. Furthermore, the need for systemic treatment was higher in smokers.Öğe Evaluation of Testicular Self-examination Technique and Testis Cancer Knowledge Levels of Final-year Medical Students(Galenos Yayincilik, 2019) Uyar, Mehmet; Yildirim, Elif Nur; Sahin, Tahir KemalObjective: The aim of this study was to evaluate the adequacy of knowledge regarding testicular self-examination (TSE) in final-year medical students and determine the TSE performance rate among male students. Materials and Methods: This cross-sectional study was conducted with final-year students in the Meram Medical Faculty of Necmettin Erbakan University in the 2015-2016 academic year. The target population of the study was 233 people and all 202 people who agreed to participate in the survey were included. A data collection form consisting of 29 questions was prepared for the study and was completed under observation. Questions regarding TSE technique and knowledge of TSE and testicular cancer were scored as 1 point for each correct answer and 0 points for incorrect answers. Scores >= 6 points for TSE technique and >= 10 points for TSE and testicular cancer knowledge were regarded as adequate. Results: The mean age of the participants was 24.12 +/- 1.32 years; 44.1% were women and 89.6% were single. Nearly 25% of the students reported they knew how to perform TSE and 32.1% had performed TSE before. History of cancer in a first-degree relative was reported by 17.4% of the students, but no students had family history of testicular cancer. Fifty-three of the students who claimed to know how to perform TSE, only 34% (n=18) scored at least 6 points in the TSE technique questions. Evaluation of scores in the TSE and testicular cancer knowledge section showed that 21.3% (n=37) scored above the 10 point limit. Conclusion: In our study, it was observed that most of the final-year medical students did not have sufficient information on TSE and testicular cancer, and that TSE rates of male students were low.Öğe Is prenatal testosterone-estrogen balance associated with psoriasis?(Wiley, 2020) Ozer, Ilkay; Temiz, Selami A.; Ataseven, Arzu; Dursun, Recep; Uyar, Mehmet; Ozer, MustafaThe etiopathogenesis of psoriasis is not understood; however, psoriasis is affected by hormones, particularly the sex steroids. The second-to-fourth digit (2D:4D) ratio, which is an indicator of prenatal sex hormone balance, has been studied in various diseases that are affected by hormones. A total of 369 individuals comprising 172 patients with psoriasis and 197 healthy volunteers were included in the study. Patients with psoriasis were divided into type-1 and type-2, according to age of onset and family history. The 2D:4D ratio of both hands was recorded for all participants. Females in the psoriasis group had a lower 2D:4D ratio in both hands compared with those in the control group, with no significant difference. Males in the psoriasis group had a higher 2D:4D ratio for both hands compared with those in the control group (P= .009 andP < .001 for the right and left hands, respectively). Further, male patients with type-1 psoriasis had a lower 2D:4D ratio compared to those with type-2 psoriasis. Our results suggest that an alteration of the estrogen-testosterone balance due to prenatal testosterone activity is an independent predisposing factor for psoriasis in males.Öğe Konya il merkezindeki sağlık ocaklarının verimliliğinin değerlendirilmesi(2015) Uyar, Mehmet; Şahin, Tahir KemalAMAÇ: Sağlık Hizmetlerinde çıktıları ölçmek zordur. Birinci basamak sağlık kuruluşlarında verimlilik ve performans ölçümünde kullanılacak standart bir yöntem ve araç yoktur. Birinci basamak sağlık kuruluşlarının performans değerlendirmesi kaynakların etkili kullanımı konusunda yol gösterici olabilir. YÖNTEM: Tanımlayıcı tipte olan bu çalışma ile Konya il merkezinde faal olarak çalışan 33 sağlık ocağının verimliliklerinin değerlendirilmesi amaçlanmıştır. Performans değerlendirmesinde girdi yönelimli Veri Zarflama Analizi (VZA) yöntemi kullanılmıştır. Teknik verimlilik puanı "1" olan sağlık ocakları verimli olarak kabul edilmiştir. BULGULAR: Çalışmada uygulanan modele göre sağlık ocaklarının 13 (%39)'ü teknik olarak tam verimli çıkmıştır. 5 sağlık ocağının teknik verimlilik puanı 0,900 ile 0,999 arasında çıkmıştır. Girdi fazlalığı olan sağlık ocağı sayısı çıktı eksiği olan sağlık ocağı sayısından fazladır. SONUÇ: Sağlık ocakları arasında verimlilik farkı çıktılardan ziyade girdilerdeki farktan kaynaklanmaktadır. Sağlık hizmeti yöneticileri benzer yöntemlerle aynı veya farklı değişkenleri kullanarak sağlık kuruluşlarının performanslarını değerlendirebilir ve sağlık kuruluşlarında verimli-verimsiz ayrımı yaparak, verimsizlik nedenlerini ortaya koyabilir. Bu yöntem hizmetlerin planlanmasında yöneticilere yol gösterici olabilir.Öğe Konya-Meram’da Dumansız Hava Sahası Denetimi Yapan Ekiplerin Karşılaştıkları Sorunlar(2017) Demir, Lütfi Saltuk; Tunçez, İsmail Hakkı; Durduran, Yasemin; Uyar, Mehmet; Şahin, Tahir KemalAmaç: Ülkemizde tütünle mücadele konusunda kapsamlı olarakbirçok plan ve program yürütülmekte, aynı zamanda il tütün kontrol kurulları tarafından tütün denetimleri düzenli olarak yapılmaktadır.Ancak denetimleri yapan ekipler çeşitli sorunlarla karşılaşmaktaolup, bu durum denetimlerin etkinliğini ve sürekliliğini azaltmaktadır.Bu çalışma ile dumansız hava sahası denetimi yapan ekiplerinkarşılaştıkları sorunların belirlenmesi amaçlanmıştır.Materyal ve Metot: Kesitsel tipte olan bu çalışmaya, Konya iliMeram ilçesinde son bir yıl içerisinde dumansız hava sahası denetimiyapan ve çalışmaya katılmayı kabul eden Toplum Sağlığı Merkezi,İlçe Emniyet Müdürlüğü ve Belediye Zabıtası çalışanları dahil edildi.Katılımcılara literatür taranarak ve ilgili mevzuat incelenerek araştırmacılartarafından hazırlanan veri toplama formu uygulandı. Elde edilenverilerin analizi bilgisayarda istatistik paket programı kullanılarakgerçekleştirildi.Bulgular: Araştırmaya katılanların %40,0’ı Emniyet Müdürlüğü,%35,0’i Belediye Başkanlığı, kalan %25,0’i ise Toplum SağlığıMerkezi’nde çalışmaktaydı. Son bir yıl içinde denetim ekibininyaptığı denetim sayısı ortancası 100 (2–2000) idi. Toplum SağlığıMerkezi’nde çalışan personelin Emniyet ve Belediye ekiplerindendaha fazla denetim yaptığı tespit edildi. Denetimler esnasındaherhangi bir sorunla karşılaştığını ifade eden katılımcıların oranı%49,0’du. En çok sorunla karşılaşan grubun Toplum SağlığıMerkezi çalışanları olduğu saptandı. Tütün denetimi yapan katılımcılarınen çok karşılaştığı üç sorun sırasıyla; sözel saldırı (%44,9),tehdit edilme (%22,4) ve fiziksel saldırı (%14,3) olarak tespit edildi.Sonuç: İş yükünün büyük çoğunluğunu üstlenen ve aynı zamandadaha çok sorunla karşılaştığı düşünülen Toplum Sağlığı Merkeziekiplerine tütün denetimleri esnasında polis veya jandarma ekiplerinineşlik etmesi faydalı olacaktır.Öğe Mean platelet volume, neutrophil to lyphocyte ratio and platelet to lymphocyte ratio in psoriasis(Deri Zuhrevi Hastaliklar Dernegi, 2015) Unal, Mehmet; Kucuk, Adem; Unal, Gulbahar Urun; Balevi, Sukru; Tol, Huseyin; Aykol, Caner; Uyar, MehmetBackground and Design: It has been demonstrated that neutrophil and platelet count to lymphocyte ratio may be a useful predictor of systemic inflammation and with prognosis of many cardiovascular diseases, malignancies and chronic inflammatory diseases. To the best of our knowledge, there are no studies investigating neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR) and mean platelet volume (MPV) values together within the context of psoriasis, a chronic and systemic inflammatory disease. Materials and Methods: In this study, we evaluated 320 patients with psoriasis vulgaris followed up in our outpatient clinic and 200 healthy controls. Results: Leukocyte, neutrophil, platelet, MPV, NLR and PLR values in patients with psoriasis were significantly higher, and lymphocyte count, on the other hand, was significantly lower than in controls. No significant difference was found in MPV, NLR and PLR values between patients with or without a family history and nail and joint involvement. Conclusions: These parameters may be used as cheap and easily applicable methods in predicting which psoriasis patients are under the risk of cardiovascular disease. PLR is a better inflammation marker than MPV and NLR in patients with psoriasis. We did not observe a significant relationship of MPV, NLR and PLR values with disease characteristics, such as severity of disease, joint involvement, nail involvement and duration of disease in patients with psoriasis. Therefore, we believe that there is little information on the extent to which MPV, NLR and PLR might be useful regarding these characteristics.Öğe Neuroprotective Effects of Tocilizumab on Experimentally-Induced Spinal Cord Ischemia-Reperfusion Injury(Elsevier Science Inc, 2019) Karatas, Yasar; Erdi, Mehmet Fatih; Kaya, Bulent; Keskin, Fatih; Cuce, Gokhan; Kilinc, Ibrahim; Uyar, MehmetOBJECTIVES: We aimed to evaluate neuroprotective effects of tocilizumab on spinal cord ischemia-reperfusion (I/R) injury. Our study design was an experimental rabbit spinal cord I/R injury model, and the setting was at the Animal Research Laboratory, Necmettin Erbakan University, Meram School of Medicine, Konya, Turkey. METHODS: Twenty-four adult New Zealand rabbits were randomly divided into 3 groups: Group 1, control group (n = 8); Group 2, I/R group, and Group 3 (n = 8) I/R injury D tocilizumab (4 mg/kg, ip) treatment group. Spinal cord I/R injury repair was performed by infrarenal aortic cross clamping. On neurologic evaluation, spinal cord tissue plasma tumor necrosis factor alpha (TNFa), total antioxidant status (TAS), total oxidant status (TOS), thiobarbituric acid reactive substances (TBARS), interleukin 6 (IL-6), interleukin 10 (IL-10) levels were analyzed. Spinal cord neuronal damage score and apoptotic cell count were also investigated. RESULTS: I/R injury significantly increases the plasma and spinal cord tissue TNFa, TOS, TBARS, and IL-6 levels and decreases the plasma and spinal cord tissue TAS and IL-10 levels. Tocilizumab treatment significantly reduces the plasma and spinal cord tissue TNF alpha, TOS, TBARS, IL-6 levels and increases plasma and tissue TAS and IL-10 levels. I/R injury significantly increases spinal cord neuronal damage score and apoptotic cell count. Tocilizumab treatment significantly reduces spinal cord neuronal damage score and apoptotic cell count. Neurologic examination scores at 24, 48, and 72 hours were significantly better in the treatment group when compared with the I/R group. CONCLUSIONS: This study shows significant neuroprotective effects of tocilizumab on rabbit spinal cord I/R injury.Öğe Patient Knowledge, Attitudes, and Behaviors Associated with Organ Donation(Int Scientific Information, Inc, 2019) Uyar, Mehmet; Demir, Lutfi Saltuk; Durduran, Yasemin; Evci, Reyhan; Ardic, Zehra Diker; Sahin, Tahir KemalBackground: This study compared the knowledge, attitudes, and behaviors associated with organ donation and transplantation among patients undergoing dialysis versus those visiting family health centers (FHCs). Material/Methods: This cross-sectional study included patients undergoing hemodialysis treatment at the Meram Medical Faculty and those visiting FHCs in Meram district for other reasons. Results: The study participants were 128 individuals visiting FHCs and 111 patients undergoing dialysis. Of these, 169 individuals (70.7%) correctly answered the question What is brain death? The knowledge level in the FHC group was higher than that in the dialysis group. Less than half of the individuals indicated willingness to donate an organ. Furthermore, subjects in the dialysis group were more likely than those in the FHC group to answered no to the question Would you be willing to donate an organ to someone of a different religion? Conclusions: Positive attitude towards organ transplantation and donation does not necessarily reflect positive behavior these 2 groups.
