İnfertil Kadınlarda Metabolik Sendrom ve Uzun Dönem Kronik Sağlık Sorunları Sıklığı
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Tarih
2017
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Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
İnfertilite hiç korunmadan düzenli cinsel ilişkiye rağmen bir yıl içinde gebelik olmaması durumudur. Bu çalışmada infertil kadın hastalarda metabolik sendrom (MetS) görülme sıklığı ve uzun dönem kronik sağlık sorunlarının değerlendirilmesi amaçlanmıştır. Yöntemler: Kesitsel ve analitik tipteki bu çalışma aile hekimliği polikliniğine kadın infertilitesi yakınması ile sağlık raporu almak için mü- racaat eden 701 kadının dosyaları retrospektif olarak incelenerek yapılmıştır. Dosyalardan elde edilen bilgilere göre katılımcıların ağırlık, boy, bel çevresi, kan basıncı ve laboratuar sonuçları kaydedilmiştir. Ulusal Kolesterol Eğitim Programı Erişkin Tedavi Paneli III - National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) de yayınlanan kriterlere göre MetS varlığı değerlendirilmiştir. Bulgular: Araştırmaya dahil edilen 701 infertil kadının yaş ortalaması 29,94,4 (20-42) yıl, %81,6'sı (n572) ev hanımı, %56,8'i (n398) ilköğretim ve altı eğitimli olduğu tespit edilmiştir. Hastaların %78,9'u (n553) primer infertilite nedeniyle başvurmuştur. Çalışmamıza katı- lan hastalarda MetS sıklığı %19,8 bulunmuştur. Obez olanlarda MetS gelişme sıklığı obez olmayanlara göre 6,389 kat daha fazla saptanmıştır [OR6,389, %95 CI;(4,260-9,581)], bu fark istatistiksel olarak anlamlı derecede yüksek bulunmuştur (p0,001). MetS bileşenleri içinde en sık trigliserid (TG) yüksekliği (%59,6) ve açlık kan glukozu yüksekliği (%55,0) tespit edilmiştir. Hipertansiyon (HT) tespit edilen hastaların %50,3'ünde MetS saptanmıştır. Kadınların %22,8'inde hipotiroidi ve %2,7'sinde brucella seropozitifliği tespit edilmiştir. Sonuç: İnfertilite ile ilişkili değiştirilebilir faktörler arasında yer alan obezite, uzun vadeli sağlık sorunları, sigara ve bazı bulaşıcı hastalıkların infertilite tedavisi öncesi ekarte edilmesi gerekmektedir. Dengeli ve doğru beslenme, fiziksel aktivite, sigara ve alkol bağımlılığı ile mü- cadele gibi sağlıklı yaşam tarzı değişiklikleri obezite riskini azaltacak, infertilite tedavi şansını arttıracaktır.
Infertility is a condition wherein there is no pregnancy within 1 year despite regular sexual intercourse without birth control. The aim of this study was to evaluate the incidence of metabolic syndrome (MetS) and chronic long-term health problems in infertile female patients. Methods: This cross-sectional and analytical study was retrospectively conducted on 701 women who applied to family medicine outpatient clinic and received a medical report with the complaint of female infertility. The weight, height, waist circumference, blood pressure, and laboratory results of subjects were recorded from the information in the files. MetS was diagnosed according to the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) guideline. Results: The mean age of the 701 infertile women in the study was 29.94.4 (20–42) years; 81.6% (n572) were housewives and 56.8% (n398) completed primary school and were undergraduates. Of the patients, 78.9% (n553) were admitted due to primary infertility. The incidence of MetS was 19.8% in the subjects of this study. The risk of MetS was 6,389 times higher in obese than in non-obese individuals [odds ratio (OR)6,389; %95 confidence interval (CI): (4,260–9,581)], and this difference was statistically significant (p0.001). The most common MetS components were triglyceride elevation (59.6%) and fasting blood glucose (55.0%). MetS was detected in 50.3% of hypertensive patients. Of the participants, 22.8% had hypothyroidism and 2.7% were found to have brucella seropositivity. Conclusion: Obesity, long-term health problems, smoking, and some infectious diseases, which are among the replaceable factors associated with infertility, should be excluded before infertility treatment. Healthy lifestyle changes such as well-balanced and correct nutrition, physical activity, giving up smoking and alcohol will reduce the risk of obesity and increase the chances of infertility treatment.
Infertility is a condition wherein there is no pregnancy within 1 year despite regular sexual intercourse without birth control. The aim of this study was to evaluate the incidence of metabolic syndrome (MetS) and chronic long-term health problems in infertile female patients. Methods: This cross-sectional and analytical study was retrospectively conducted on 701 women who applied to family medicine outpatient clinic and received a medical report with the complaint of female infertility. The weight, height, waist circumference, blood pressure, and laboratory results of subjects were recorded from the information in the files. MetS was diagnosed according to the National Cholesterol Education Program (NCEP) Adult Treatment Panel III (ATP III) guideline. Results: The mean age of the 701 infertile women in the study was 29.94.4 (20–42) years; 81.6% (n572) were housewives and 56.8% (n398) completed primary school and were undergraduates. Of the patients, 78.9% (n553) were admitted due to primary infertility. The incidence of MetS was 19.8% in the subjects of this study. The risk of MetS was 6,389 times higher in obese than in non-obese individuals [odds ratio (OR)6,389; %95 confidence interval (CI): (4,260–9,581)], and this difference was statistically significant (p0.001). The most common MetS components were triglyceride elevation (59.6%) and fasting blood glucose (55.0%). MetS was detected in 50.3% of hypertensive patients. Of the participants, 22.8% had hypothyroidism and 2.7% were found to have brucella seropositivity. Conclusion: Obesity, long-term health problems, smoking, and some infectious diseases, which are among the replaceable factors associated with infertility, should be excluded before infertility treatment. Healthy lifestyle changes such as well-balanced and correct nutrition, physical activity, giving up smoking and alcohol will reduce the risk of obesity and increase the chances of infertility treatment.
Açıklama
Anahtar Kelimeler
Metabolik sendrom, Kadın infertilitesi, Obezite, Metabolic syndrome, Female ınfertility, Obesit
Kaynak
İstanbul Medical Journal
WoS Q Değeri
Scopus Q Değeri
Cilt
18
Sayı
4
Künye
Kutlu, R., Görkemli, H., Işıklar Özberk, D. (2017). İnfertil kadınlarda metabolik sendrom ve uzun dönem kronik sağlık sorunları sıklığı. İstanbul Medical Journal, 18, 4, 210-217.
